Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
about
A loss of FUS/TLS function leads to impaired cellular proliferationNEK1 variants confer susceptibility to amyotrophic lateral sclerosisLiquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation.Long noncoding RNA SchLAH suppresses metastasis of hepatocellular carcinoma through interacting with fused in sarcoma.ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function.Changes in the Expression of FUS/TLS in Spinal Cords of SOD1 G93A Transgenic Mice and Correlation with Motor-Neuron Degeneration.Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage.FUS Mislocalization and Vulnerability to DNA Damage in ALS Patients Derived hiPSCs and Aging Motoneurons.Sequestration of PRMT1 and Nd1-L mRNA into ALS-linked FUS mutant R521C-positive aggregates contributes to neurite degeneration upon oxidative stress.Compromised MAPK signaling in human diseases: an update.Roles for RNA-binding proteins in development and disease.Genetics of FTLD: overview and what else we can expect from genetic studies.Stress granules at the intersection of autophagy and ALS.Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies.TDP-43/FUS in motor neuron disease: Complexity and challenges.Linking amyotrophic lateral sclerosis and spinal muscular atrophy through RNA-transcriptome homeostasis: a genomics perspective.Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand.Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity.Autophagy meets fused in sarcoma-positive stress granules.Targeted Genetic Screen in Amyotrophic Lateral Sclerosis Reveals Novel Genetic Variants with Synergistic Effect on Clinical Phenotype.The hnRNP RALY regulates transcription and cell proliferation by modulating the expression of specific factors including the proliferation marker E2F1.DNA plasticity and damage in amyotrophic lateral sclerosis.The Role of Post-Translational Modifications on Prion-Like Aggregation and Liquid-Phase Separation of FUS.Linking hnRNP Function to ALS and FTD Pathology.
P2860
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P2860
Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
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2014 nî lūn-bûn
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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2014 թվականի հունիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
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Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
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Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
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Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
@ast
Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
@en
Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
@nl
prefLabel
Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
@ast
Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
@en
Functions of FUS/TLS from DNA repair to stress response: implications for ALS.
@nl
P2860
P921
P356
P1433
P1476
Functions of FUS/TLS from DNA repair to stress response: implications for ALS
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P2093
Catherine L Ward
Reddy Ranjith Kumar Sama
P2860
P356
10.1177/1759091414544472
P577
2014-06-01T00:00:00Z