Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop. - Wikidata - awgldk - TriplyDB

Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop.

Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop.

http://www.wikidata.org/entity/Q34306877

about

Possible future monoclonal antibody (mAb)-based therapy against arbovirus infections Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus Rapid isolation of dengue-neutralizing antibodies from single cell-sorted human antigen-specific memory B-cell cultures A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes Dengue E Protein Domain III-Based DNA Immunisation Induces Strong Antibody Responses to All Four Viral Serotypes Viral membrane fusion and nucleocapsid delivery into the cytoplasm are distinct events in some flaviviruses Systematic Bioinformatic Approach for Prediction of Linear B-Cell Epitopes on Dengue E and prM Protein A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface Dengue virus antibodies enhance Zika virus infection Immune activation alters cellular and humoral responses to yellow fever 17D vaccine Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits Variable inhibition of Zika virus replication by different Wolbachia strains in mosquito cell cultures Temperature-dependent folding allows stable dimerization of secretory and virus-associated E proteins of Dengue and Zika viruses in mammalian cells.The potent and broadly neutralizing human dengue virus-specific monoclonal antibody 1C19 reveals a unique cross-reactive epitope on the bc loop of domain II of the envelope protein Atomic-level functional model of dengue virus Envelope protein infectivity.A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins Fluorescently labeled dengue viruses as probes to identify antigen-specific memory B cells by multiparametric flow cytometry.A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus.Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice Complexity of Neutralizing Antibodies against Multiple Dengue Virus Serotypes after Heterotypic Immunization and Secondary Infection Revealed by In-Depth Analysis of Cross-Reactive Antibodies Japanese encephalitis vaccine-facilitated dengue virus infection-enhancement antibody in adults.A game of numbers: the stoichiometry of antibody-mediated neutralization of flavivirus infection.Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection.DENV-2 subunit proteins fused to CR2 receptor-binding domain (P28)-induces specific and neutralizing antibodies to the Dengue virus in mice.Therapeutic antibodies as a treatment option for dengue fever.DNA-immunisation with dengue virus E protein domains I/II, but not domain III, enhances Zika, West Nile and Yellow Fever virus infection.Discovery of protective B-cell epitopes for development of antimicrobial vaccines and antibody therapeutics.Receptors and routes of dengue virus entry into the host cells.Genetic epidemiology of dengue viruses in phase III trials of the CYD tetravalent dengue vaccine and implications for efficacy Complexity of Human Antibody Response to Dengue Virus: Implication for Vaccine Development.A mouse monoclonal antibody against dengue virus type 1 Mochizuki strain targeting envelope protein domain II and displaying strongly neutralizing but not enhancing activity.Structure-function analysis of hepatitis C virus envelope glycoproteins E1 and E2.Adjuvant-Mediated Epitope Specificity and Enhanced Neutralizing Activity of Antibodies Targeting Dengue Virus Envelope Protein Generation and characterization of cross neutralizing human monoclonal antibody against 4 serotypes of dengue virus without enhancing activity.The hallmarks of cell-cell fusion.Development of Antibody Therapeutics against Flaviviruses.Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein.Wolbachia wStri Blocks Zika Virus Growth at Two Independent Stages of Viral Replication.Modulation of Dengue/Zika Virus Pathogenicity by Antibody-Dependent Enhancement and Strategies to Protect Against Enhancement in Zika Virus Infection.Potent Neutralization Ability of a Human Monoclonal Antibody Against Serotype 1 Dengue Virus.

P2860

Q24289014-30849478-78AE-41E0-A7DC-66AED4BBD6CE Q25161212-292ABCAE-BF93-4015-9EF0-7F1A19707758 Q26700070-CD0F130F-19F6-477F-B029-53A5F023F558 Q26860116-ACAE86AE-E35A-44BC-8BB6-E43135D2BA49 Q27304342-94E7921F-D8E4-4CDC-BE08-59AF623FB444 Q27333686-96146796-2612-4348-BE2D-8ABF48C67898 Q27468788-FADBA6FA-6DED-44B7-B66C-148E45E20BFC Q27681319-AE19FA5D-4DAC-4D32-A97D-B9FE6EB1A993 Q28353949-AAE52C4A-0A86-4C70-88C0-09CA96D862CC Q28388716-D12C39B2-006F-4C3B-9346-9DD17F3CE0E5 Q28602816-FADEFF2B-CBC3-4F30-AAA6-82FC710C0D1C Q29587266-9F01391B-DD43-4CC6-9D48-B86F81666914 Q33681310-FCB37370-82D3-47F8-A3FD-55D057568696 Q34386384-A762B41D-1C8C-4489-8ED5-9712842B8D98 Q35026063-7EA7BC4C-77AF-42A1-A5EE-094F748B20D1 Q35138111-0BD2AB4D-E283-415B-BCAF-9A3CDBBF8502 Q35632639-330E7DDD-FADF-4182-8BA3-542BC6FC7A2A Q35654743-B39BCCBC-2E7E-4B5C-95E4-FBE2BE937245 Q35659085-5364360C-5FAD-48C9-93F4-FF81B39F105C Q35758626-FC971CC6-CFD2-41E8-BAC6-B7324B25E196 Q36166556-91E93D10-8920-4999-82C9-89E6AD65E104 Q37012203-24F2A676-74B1-47A7-92B7-5151329B3D56 Q37123259-4DAE733D-7BBC-4A8B-BD35-F275B30C174B Q37694852-4F39E8EA-5720-436F-ADA2-1CDEC1C97C27 Q38149195-53919E0D-1A1B-4CEE-A91A-E593F171900C Q38157397-035F64E0-D6A6-4E65-B155-A61F6DAC8586 Q38161994-3A61BD91-0597-44E5-9282-6E41F184A75C Q38366005-66B5479F-E925-4F22-8ACE-F1C711431B10 Q39375868-DBBC0478-0DD2-48D6-94FD-E70B777DE6B8 Q39535403-EE946BAA-815F-4072-B9D1-7AAD0159508D Q39611340-3E1BE0F2-AFA7-448F-A6CD-3A6CB65132D9 Q40189989-9A440CD1-70A4-4947-A028-C0C1434E2E8D Q41921198-C40C3207-F866-4ADB-AE50-85C1399D76F3 Q45324646-3C6F8142-4776-4856-9471-046A39550F8C Q47279331-1DAC7698-7606-4DDD-AB72-7442F267B84A Q47558158-D3C69B51-18F0-4665-A0B6-45C48CAC01AB Q50099498-2D3B3C7D-7116-4377-8D8C-32D1A67B52F2 Q54201982-44398797-8B04-4F7F-A5A8-895C4F6492A4 Q54217627-B457BC89-2F6A-4D42-97D5-4E748B0AAC99 Q55338916-2B34CAB5-CF03-466E-9955-85FCC546F447

P2860

Mechanistic study of broadly neutralizing human monoclonal antibodies against dengue virus that target the fusion loop.

http://www.wikidata.org/entity/Q34306877

description

2012 nî lūn-bûn

@nan

2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Mechanistic study of broadly n ...... s that target the fusion loop.

@ast

Mechanistic study of broadly n ...... s that target the fusion loop.

@en

Mechanistic study of broadly n ...... s that target the fusion loop.

@nl

type

label

Mechanistic study of broadly n ...... s that target the fusion loop.

@ast

Mechanistic study of broadly n ...... s that target the fusion loop.

@en

Mechanistic study of broadly n ...... s that target the fusion loop.

@nl

prefLabel

Mechanistic study of broadly n ...... s that target the fusion loop.

@ast

Mechanistic study of broadly n ...... s that target the fusion loop.

@en

Mechanistic study of broadly n ...... s that target the fusion loop.

@nl

P1433

Q34306877-2176426A-AD8F-4D1E-AE9F-81EC871BB0D4

P1476

Q34306877-D5C6C20B-6137-4ABE-9B15-E7CE396C3ECB

P2093

Q34306877-0A2C7748-3F48-48FB-A610-CA5501085DE4

Q34306877-2B787E00-039F-4C61-96A0-741DC0A94036

Q34306877-3B5BA6B4-CCD4-444D-AB52-E699E198C024

Q34306877-3F7A2D1B-B4A5-47F6-ACAA-1537E49BDED9

Q34306877-72ADF75D-AD08-408F-B9AE-CFFBA845E7C7

Q34306877-864AAE69-D4C9-426D-B9C8-2E8917FF13BE

Q34306877-94FDE5FE-4FF6-41C2-A004-90F694730F96

Q34306877-9CB100C5-C4BB-4F60-A6C2-3AF842809670

Q34306877-9DED6919-C41F-445A-924B-223F7CB6E174

Q34306877-ABBF1DB6-9F0E-45AD-94B9-55A9F83FCB62

P2860

Q34306877-0020FA8B-E7AB-4647-A4A4-483E8EDA7F82

Q34306877-04E27C41-D36B-4C49-A039-F5AD8B1B2721

Q34306877-0828F301-7DBE-452C-81DA-12AAC04905B9

Q34306877-0A7310BA-F64D-4CD5-A17D-FBCDC93F3EF6

Q34306877-0AC4701A-F822-4372-8534-F782A4E703F9

Q34306877-0B6A8BE6-EFF2-4E3C-8B36-7D25668DADC0

Q34306877-0F5132D7-3199-44D9-A667-1C88E62AFDED

Q34306877-107DE0C4-832D-4014-8DEC-4819CAE1C92D

Q34306877-122DE537-5856-49BA-85E9-CE639B990596

Q34306877-128741A0-C1F5-4576-9EC0-123C030A954C

P304

Q34306877-94D3E9E5-65E8-4C92-ACA0-86BB3F8F3903

P31

Q34306877-B4E081E5-01BA-473C-ACA8-50856D7B80A6

P356

Q34306877-8E71ABCC-C616-4EDB-8C61-F29B031002C5

P407

Q34306877-C9269500-D0F5-4BCB-8C59-7BD72454112A

P433

Q34306877-9BA2AD9E-1978-4E9A-AFCB-7AD61F8EBEF6

P478

Q34306877-0C1D25F3-4A81-4113-A626-1DF2B607CCA1

P50

Q34306877-8DBFACA1-30E3-47AD-9B4F-9FF5A8105EB3

Q34306877-A6E6DE65-3586-41C7-8489-382EA4764DFC

P577

Q34306877-10B99DFA-FF3E-42B5-BB12-89F3F32CAD1F

P5875

Q34306877-BB82B30B-3236-41EC-9B19-20AB4950BEB9

P698

Q34306877-49F2FA1C-A414-41E2-9A6C-653DB4716D99

P921

Q34306877-293E77A6-A714-4E92-AC05-9B84799C014A

Q34306877-2F019898-3F6E-4735-AE0C-BC06C7CBF80F

Q34306877-EFB5A97E-9C8C-430A-A8EA-6B1F2D522C6A

P932

Q34306877-0B0EB354-D153-4140-9115-B3985C9F6DBF

P356

P1433

Journal of Virology

P1476

Mechanistic study of broadly n ...... s that target the fusion loop.

@en

P2093

Amanda S Graham

http://www.w3.org/2001/XMLSchema#string

Benjamin J Doranz

http://www.w3.org/2001/XMLSchema#string

Cindo O Nicholson

http://www.w3.org/2001/XMLSchema#string

Dawne K Rowe

http://www.w3.org/2001/XMLSchema#string

Elena Zaitseva

http://www.w3.org/2001/XMLSchema#string

Greg Hogancamp

http://www.w3.org/2001/XMLSchema#string

James E Robinson

http://www.w3.org/2001/XMLSchema#string

John S Schieffelin

http://www.w3.org/2001/XMLSchema#string

Joshua M Costin

http://www.w3.org/2001/XMLSchema#string

Kristen M Kahle

http://www.w3.org/2001/XMLSchema#string

P2860

Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention

Structure of dengue virus: implications for flavivirus organization, maturation, and fusion

Monoclonal Antibodies That Bind to Domain III of Dengue Virus E Glycoprotein Are the Most Efficient Blockers of Virus Adsorption to Vero Cells

A ligand-binding pocket in the dengue virus envelope glycoprotein

Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking.

Type- and Subcomplex-Specific Neutralizing Antibodies against Domain III of Dengue Virus Type 2 Envelope Protein Recognize Adjacent Epitopes

Dengue viruses and mononuclear phagocytes. I. Infection enhancement by non-neutralizing antibody

A Tetravalent Dengue Vaccine Based on a Complex Adenovirus Vector Provides Significant Protection in Rhesus Monkeys against All Four Serotypes of Dengue Virus

Antibodies to Envelope Glycoprotein of Dengue Virus during the Natural Course of Infection Are Predominantly Cross-Reactive and Recognize Epitopes Containing Highly Conserved Residues at the Fusion Loop of Domain II

Viral membrane fusion

P304

52-66

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/JVI.02273-12

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

87

http://www.w3.org/2001/XMLSchema#string

P50

Scott F Michael

P577

2012-10-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

232281558

http://www.w3.org/2001/XMLSchema#string

P698

23077306

http://www.w3.org/2001/XMLSchema#string

P921

membrane fusion involved in viral entry into host cell

P932

3536401

http://www.w3.org/2001/XMLSchema#string