Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
about
Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathiesSynergic prodegradative activity of Bicalutamide and trehalose on the mutant androgen receptor responsible for spinal and bulbar muscular atrophy.Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia.Modulating the Amyloidogenesis of α-SynucleinClearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy.Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicityAberrant autophagy and parkinsonism: does correction rescue from disease progression?Recent advances in autophagy-based neuroprotection.Neuroprotective Natural Products for the Treatment of Parkinson's Disease by Targeting the Autophagy-Lysosome Pathway: A Systematic Review.Therapeutic potential of autophagy-enhancing agents in Parkinson's disease.Trehalose alleviates PC12 neuronal death mediated by lipopolysaccharide-stimulated BV-2 cells via inhibiting nuclear transcription factor NF-κB and AP-1 activation.Trehalose does not improve neuronal survival on exposure to alpha-synuclein pre-formed fibrils.Curcumin ameliorates the neurodegenerative pathology in A53T α-synuclein cell model of Parkinson's disease through the downregulation of mTOR/p70S6K signaling and the recovery of macroautophagy.Treatment with Trehalose Prevents Behavioral and Neurochemical Deficits Produced in an AAV α-Synuclein Rat Model of Parkinson's Disease.Proteasome inhibitor-induced autophagy in PC12 cells overexpressing A53T mutant α-synuclein.Trehalose delays the progression of amyotrophic lateral sclerosis by enhancing autophagy in motoneurons.Is trehalose an autophagic inducer? Unraveling the roles of non-reducing disaccharides on autophagic flux and alpha-synuclein aggregation.Tetrahydroxystilbene glucoside inhibits α-synuclein aggregation and apoptosis in A53T α-synuclein-transfected cells exposed to MPP.Trehalose Inhibits A53T Mutant α-Synuclein Overexpression and Neurotoxicity in Transduced PC12 Cells.Cypermethrin Activates Autophagosome Formation Albeit Inhibits Autophagy Owing to Poor Lysosome Quality: Relevance to Parkinson's Disease.Ginkgolide K promotes the clearance of A53T mutation alpha-synuclein in SH-SY5Y cells.Deciphering the roles of trehalose and Hsp104 in the inhibition of aggregation of mutant huntingtin in a yeast model of Huntington's disease.Salidroside Promotes the Pathological α-Synuclein Clearance Through Ubiquitin-Proteasome System in SH-SY5Y Cells.
P2860
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P2860
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@ast
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@en
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@nl
type
label
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@ast
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@en
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@nl
prefLabel
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@ast
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@en
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@nl
P2093
P2860
P921
P1476
Effect of trehalose on PC12 cells overexpressing wild-type or A53T mutant α-synuclein.
@en
P2093
Dan-Mei Lan
Feng-Tao Liu
Hui-Min Ren
Jian-Jun Wu
Yu-Ping Jiang
Zhen-Yu Yue
Zheng-Tong Ding
P2860
P2888
P304
P356
10.1007/S11064-012-0823-0
P577
2012-06-17T00:00:00Z
P6179
1011759733