The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5.
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Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit bindingEvaluation of rhesus monkey and guinea pig hepatic cytosol fractions as models for human aldehyde oxidase.Enzymatic conversion of 6-nitroquinoline to the fluorophore 6-aminoquinoline selectively under hypoxic conditions.Strategies for a comprehensive understanding of metabolism by aldehyde oxidase.Metabotropic glutamate receptor 5-negative allosteric modulators for the treatment of psychiatric and neurological disorders (2009-July 2013).The role of drug metabolizing enzymes in clearance.Evaluating the Disposition of a Mixed Aldehyde Oxidase/Cytochrome P450 Substrate in Rats with Attenuated P450 Activity.Discovery of VU0409106: A negative allosteric modulator of mGlu5 with activity in a mouse model of anxietyStructure-Based Drug Design of Novel, Potent, and Selective Azabenzimidazoles (ABI) as ATR Inhibitors.Discovery of VU0431316: a negative allosteric modulator of mGlu5 with activity in a mouse model of anxiety.Discovery of imidazo[1,2-a]-, [1,2,4]triazolo[4,3-a]-, and [1,2,4]triazolo[1,5-a]pyridine-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5.Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation.Sex-related effects of imidacloprid modulated by piperonyl butoxide and menadione in rats. Part II: genotoxic and cytotoxic potential.
P2860
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P2860
The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5.
description
2012 nî lūn-bûn
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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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name
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@ast
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@en
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@nl
type
label
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@ast
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@en
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@nl
prefLabel
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@ast
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@en
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@nl
P2093
P2860
P50
P356
P1476
The role of aldehyde oxidase a ...... glutamate receptor subtype 5.
@en
P2093
Alice L Rodriguez
Andrew S Felts
Anna L Blobaum
Brittney S Bates
Carrie K Jones
Daryl F Venable
Donald Stec
Frank W Byers
J Scott Daniels
Jason Manka
P2860
P304
P356
10.1124/DMD.112.046136
P577
2012-06-18T00:00:00Z