The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination. - Wikidata - awgldk - TriplyDB

The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination.

The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination.

http://www.wikidata.org/entity/Q34309225

about

HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZ Controlling DNA-End Resection: An Emerging Task for Ubiquitin and SUMO SUMO-mediated regulation of DNA damage repair and responses Ubiquitylation, neddylation and the DNA damage response Identification of TRIM27 as a novel degradation target of herpes simplex virus 1 ICP0.Effect of a poly(ADP-ribose) polymerase-1 inhibitor against esophageal squamous cell carcinoma cell lines.Carriage of NBN polymorphisms and acute leukemia risk Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.Reading, writing, and repair: the role of ubiquitin and the ubiquitin-like proteins in DNA damage signaling and repair.The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.Rad18 and Rnf8 facilitate homologous recombination by two distinct mechanisms, promoting Rad51 focus formation and suppressing the toxic effect of nonhomologous end joining.NRAGE is involved in homologous recombination repair to resist the DNA-damaging chemotherapy and composes a ternary complex with RNF8-BARD1 to promote cell survival in squamous esophageal tumorigenesis.Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4.Meta-analysis of DNA double-strand break response kinetics.RNF8- and Ube2S-Dependent Ubiquitin Lysine 11-Linkage Modification in Response to DNA Damage.Hsp90α regulates ATM and NBN functions in sensing and repair of DNA double-strand breaks.Mitotic and Meiotic Functions for the SUMOylation Pathway in the Caenorhabditis elegans Germline.The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.

P2860

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P2860

The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination.

http://www.wikidata.org/entity/Q34309225

description

2012 nî lūn-bûn

@nan

2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

The RING finger protein RNF8 u ...... r by homologous recombination.

@ast

The RING finger protein RNF8 u ...... r by homologous recombination.

@en

The RING finger protein RNF8 u ...... r by homologous recombination.

@nl

type

label

The RING finger protein RNF8 u ...... r by homologous recombination.

@ast

The RING finger protein RNF8 u ...... r by homologous recombination.

@en

The RING finger protein RNF8 u ...... r by homologous recombination.

@nl

prefLabel

The RING finger protein RNF8 u ...... r by homologous recombination.

@ast

The RING finger protein RNF8 u ...... r by homologous recombination.

@en

The RING finger protein RNF8 u ...... r by homologous recombination.

@nl

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P356

JBC.M112.421545

P1433

Journal of Biological Chemistry

P1476

The RING finger protein RNF8 u ...... r by homologous recombination.

@en

P2093

Aaron Aslanian

http://www.w3.org/2001/XMLSchema#string

Chi-Sheng Lu

http://www.w3.org/2001/XMLSchema#string

John R Yates

http://www.w3.org/2001/XMLSchema#string

Kwi Hye Koh

http://www.w3.org/2001/XMLSchema#string

Lan N Truong

http://www.w3.org/2001/XMLSchema#string

Linda Z Shi

http://www.w3.org/2001/XMLSchema#string

Michael W Berns

http://www.w3.org/2001/XMLSchema#string

Patty Yi-Hwa Hwang

http://www.w3.org/2001/XMLSchema#string

Tony Hunter

http://www.w3.org/2001/XMLSchema#string

Xiaohua Wu

http://www.w3.org/2001/XMLSchema#string

P2860

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

P304

43984-43994

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P31

scholarly article

P356

10.1074/JBC.M112.421545

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P407

P433

52

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P478

287

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P577

2012-10-31T00:00:00Z

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23115235

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P921

protein ubiquitination

P932

3527981

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