Cohesin proteins promote ribosomal RNA production and protein translation in yeast and human cells.
about
The Epigenetic Pathways to Ribosomal DNA SilencingMechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathiesCohesinopathies of a feather flock togetherPerturbations at the ribosomal genes loci are at the centre of cellular dysfunction and human diseaseNew insights into nucleolar structure and functionAltered RNA processing and export lead to retention of mRNAs near transcription sites and nuclear pore complexes or within the nucleolus.Cohesin: functions beyond sister chromatid cohesionCohesion promotes nucleolar structure and functionOverexpression of a truncated CTF7 construct leads to pleiotropic defects in reproduction and vegetative growth in Arabidopsis.Coordination of tRNA transcription with export at nuclear pore complexes in budding yeast.Ribosome biogenesis in skeletal development and the pathogenesis of skeletal disordersRibosomal DNA copy number loss and sequence variation in cancerTemperature-dependent regulation of rDNA condensation in Saccharomyces cerevisiaeDysregulation of RNA polymerase I transcription during disease.A sequence-specific interaction between the Saccharomyces cerevisiae rRNA gene repeats and a locus encoding an RNA polymerase I subunit affects ribosomal DNA stabilityGenome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae.Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome.L-leucine partially rescues translational and developmental defects associated with zebrafish models of Cornelia de Lange syndrome.The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability.The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity.Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndromeCohesin codes - interpreting chromatin architecture and the many facets of cohesin function.Diverse developmental disorders from the one ring: distinct molecular pathways underlie the cohesinopathies.Roberts syndrome: A deficit in acetylated cohesin leads to nucleolar dysfunction.The translational landscape of the mammalian cell cycle.Etiology and pathogenesis of the cohesinopathies.A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription.Chromatin loops and causality loops: the influence of RNA upon spatial nuclear architecture.Mms21 SUMO Ligase Activity Promotes Nucleolar Function in Saccharomyces cerevisiae.Inactivation of the budding yeast cohesin loader Scc2 alters gene expression both globally and in response to a single DNA double strand breakA genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.The SMC loader Scc2 regulates gene expression.DNA replication stress restricts ribosomal DNA copy number.Translational mechanisms at work in the cohesinopathies.The cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription.Zebrafish as a Model to Study Cohesin and Cohesinopathies.Esco2 regulates cx43 expression during skeletal regeneration in the zebrafish fin.Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast.Cohesin facilitates zygotic genome activation in zebrafish.NIPBL+/- haploinsufficiency reveals a constellation of transcriptome disruptions in the pluripotent and cardiac states.
P2860
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P2860
Cohesin proteins promote ribosomal RNA production and protein translation in yeast and human cells.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@ast
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@en
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@nl
type
label
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@ast
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@en
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@nl
prefLabel
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@ast
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@en
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@nl
P2093
P2860
P1433
P1476
Cohesin proteins promote ribos ...... tion in yeast and human cells.
@en
P2093
Alexander Garrett
Allison Peak
Andrew Box
Baoshan Xu
Bethany Harris
Brian Slaughter
Chris Seidel
Jennifer L Gerton
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002749
P577
2012-06-14T00:00:00Z