Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer therapeutics. - Wikidata - awgldk - TriplyDB

Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer therapeutics.

Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer therapeutics.

http://www.wikidata.org/entity/Q34312760

about

miRNAs Signature in Head and Neck Squamous Cell Carcinoma Metastasis: A Literature Review MicroRNAs as Important Players and Biomarkers in Oral Carcinogenesis Role of miRNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer MicroRNA-155 expression is independently predictive of outcome in chordoma.The in vitro and vivo effects of nuclear and cytosolic parafibromin expression on the aggressive phenotypes of colorectal cancer cells: a search of potential gene therapy target.MicroRNA-125a reduces proliferation and invasion of oral squamous cell carcinoma cells by targeting estrogen-related receptor α: implications for cancer therapeutics.MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.miR-155 Controls Lymphoproliferation in LAT Mutant Mice by Restraining T-Cell Apoptosis via SHIP-1/mTOR and PAK1/FOXO3/BIM Pathways Potential involvement of miR-375 in the premalignant progression of oral squamous cell carcinoma mediated via transcription factor KLF5.Overexpression of miR-155 promotes the proliferation and invasion of oral squamous carcinoma cells by regulating BCL6/cyclin D2 Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology (Review).miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC-like cells via NF-κB p65 activation Regulation of breast cancer and bone metastasis by microRNAs MicroRNAs in Head and Neck Cancer From microRNA functions to microRNA therapeutics: novel targets and novel drugs in breast cancer research and treatment (Review).CDC73 mutational status and loss of parafibromin in the outcome of parathyroid cancer.Transcriptional repression of tumor suppressor CDC73, encoding an RNA polymerase II interactor, by Wilms tumor 1 protein (WT1) promotes cell proliferation: implication for cancer therapeutics.The pivotal role of microRNA-155 in the control of cancer.MicroRNA deregulation in parathyroid tumours suggests an embryonic signature.The Role of Wnt Signaling in Squamous Cell Carcinoma.Characterization of miR-146a and miR-155 in blood, tissue and cell lines of head and neck squamous cell carcinoma patients and their impact on cell proliferation and migration.MicroRNA-155-5p is associated with oral squamous cell carcinoma metastasis and poor prognosis.Altered levels of miR-21, miR-125b-2*, miR-138, miR-155, miR-184, and miR-205 in oral squamous cell carcinoma and association with clinicopathological characteristics.MiR-155 up-regulation by LMP1 DNA contributes to increased nasopharyngeal carcinoma cell proliferation and migration.Gastric adenocarcinoma microRNA profiles in fixed tissue and in plasma reveal cancer-associated and Epstein-Barr virus-related expression patterns.Large intragenic deletion of CDC73 (exons 4-10) in a three-generation hyperparathyroidism-jaw tumor (HPT-JT) syndrome family.Biomarker MicroRNAs for Diagnosis of Oral Squamous Cell Carcinoma Identified Based on Gene Expression Data and MicroRNA-mRNA Network Analysis.A Looking-Glass of Non-coding RNAs in oral cancer.Role of non-coding RNAs in head and neck squamous cell carcinoma: A narrative review.miR-155 in cancer drug resistance and as target for miRNA-based therapeutics.MicroRNA-155 promotes apoptosis in SKOV3, A2780, and primary cultured ovarian cancer cells.MicroRNA-155 in oral squamous cell carcinoma: Overexpression, localization, and prognostic potential.

P2860

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P2860

Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer therapeutics.

http://www.wikidata.org/entity/Q34312760

description

2012 nî lūn-bûn

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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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Oncogenic microRNA-155 down-re ...... tions for cancer therapeutics.

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Oncogenic microRNA-155 down-re ...... tions for cancer therapeutics.

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Oncogenic microRNA-155 down-re ...... tions for cancer therapeutics.

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Journal of Biological Chemistry

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Oncogenic microRNA-155 down-re ...... tions for cancer therapeutics.

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Arun Kumar

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Kodaganur S Gopinath

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Mathighatta N Nagashri

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Mohammad Iqbal Rather

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Shivananda S Swamy

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P2860

Parafibromin inhibits cancer cell growth and causes G1 phase arrest

The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II

A microRNA expression signature of human solid tumors defines cancer gene targets

Accumulation of miR-155 and BIC RNA in human B cell lymphomas

The parafibromin tumor suppressor protein is part of a human Paf1 complex

MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice

Experimental validation of miRNA targets

Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development

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