Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasia
about
Short and tall stature: a new paradigm emergesFibroblast growth factor signaling in skeletal development and diseaseOptimal management of complications associated with achondroplasiaRegulation of intraocular pressure by soluble and membrane guanylate cyclases and their role in glaucomaMechanisms and models of endoplasmic reticulum stress in chondrodysplasiaA pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationAdvances in Skeletal Dysplasia GeneticsMeclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasiaProtective effects of C-type natriuretic peptide on linear growth and articular cartilage integrity in a mouse model of inflammatory arthritisFinal adult height in long-term growth hormone-treated achondroplasia patients.Recent research on the growth plate: Recent insights into the regulation of the growth plateThe Fibroblast Growth Factor signaling pathwayA human skeletal overgrowth mutation increases maximal velocity and blocks desensitization of guanylyl cyclase-B.New therapeutic targets in rare genetic skeletal diseases.FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12-ATG5 conjugate, leading to the delay of cartilage development in achondroplasiaTyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model.Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody.Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible.Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia.Fibroblast growth factor (FGF) signaling in development and skeletal diseases.Advances in treatment of achondroplasia and osteoarthritis.Therapeutic effect of CNP on renal osteodystrophy by antagonizing the FGF-23/MAPK pathway.Skeletal Dysplasias: What Every Bone Health Clinician Needs to Know.Clinical dosage of meclozine promotes longitudinal bone growth, bone volume, and trabecular bone quality in transgenic mice with achondroplasia.Short Anabolic Peptides for Bone Growth.The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.Achondroplasia: Development, pathogenesis, and therapy.Genetics of Short Stature.Mouse models for the study of cranial base growth and anomalies.Height outcome of short children with hypochondroplasia after recombinant human growth hormone treatment: a meta-analysis.Molecular therapeutic strategies for FGFR3 gene-related skeletal dysplasia.Skeletal Characterization of the Fgfr3 Mouse Model of Achondroplasia Using Micro-CT and MRI Volumetric Imaging.Meeting report of the 8th International Conference on cGMP "cGMP: generators, effectors, and therapeutic implications" at Bamberg, Germany, from June 23 to 25, 2017.Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor.Mutations in C-natriuretic peptide (NPPC): a novel cause of autosomal dominant short stature.Skeletal overgrowth-causing mutations mimic an allosterically activated conformation of guanylyl cyclase-B that is inhibited by 2,4,6,-trinitrophenyl ATP.HDAC6 deficiency or inhibition blocks FGFR3 accumulation and improves bone growth in a model of achondroplasia.Circulatory CNP Rescues Craniofacial Hypoplasia in Achondroplasia.Statin treatment rescues FGFR3 skeletal dysplasia phenotypes.Serum NT-proCNP levels increased after initiation of GH treatment in patients with achondroplasia/hypochondroplasia.
P2860
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P2860
Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasia
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Evaluation of the therapeutic ...... recapitulating achondroplasia
@ast
Evaluation of the therapeutic ...... recapitulating achondroplasia
@en
Evaluation of the therapeutic ...... recapitulating achondroplasia
@nl
type
label
Evaluation of the therapeutic ...... recapitulating achondroplasia
@ast
Evaluation of the therapeutic ...... recapitulating achondroplasia
@en
Evaluation of the therapeutic ...... recapitulating achondroplasia
@nl
prefLabel
Evaluation of the therapeutic ...... recapitulating achondroplasia
@ast
Evaluation of the therapeutic ...... recapitulating achondroplasia
@en
Evaluation of the therapeutic ...... recapitulating achondroplasia
@nl
P2093
P2860
P50
P1476
Evaluation of the therapeutic ...... recapitulating achondroplasia
@en
P2093
Arnold Munnich
Charles A O'Neill
Dan J Wendt
Emilie Mugniery
Federico Di Rocco
Florence Lorget
Laurie S Tsuruda
Sean M Bell
Sherry Bullens
P2860
P304
P356
10.1016/J.AJHG.2012.10.014
P407
P577
2012-11-29T00:00:00Z