Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction.
about
The Hedgehog Signalling Pathway in Cell Migration and Guidance: What We Have Learned from Drosophila melanogasterHedgehog is a positive regulator of FGF signalling during embryonic tracheal cell migrationLipoprotein particles are required for Hedgehog and Wingless signallingActivation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnoverOvarian Transcriptome Analysis of Portunus trituberculatus Provides Insights into Genes Expressed during Phase III and IV DevelopmentA Model of the Spatio-temporal Dynamics of Drosophila Eye Disc DevelopmentCytonemes are required for the establishment of a normal Hedgehog morphogen gradient in Drosophila epitheliaModel of the reception of hedgehog morphogen concentration gradient: comparison with an extended range of experimental data.Quantitative analysis of Hedgehog gradient formation using an inducible expression system.Hedgehog signaling establishes precursors for germline stem cell niches by regulating cell adhesion.Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicleThe role of glypicans in Wnt inhibitory factor-1 activity and the structural basis of Wif1's effects on Wnt and Hedgehog signaling.Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium.A genome-wide RNAi screen identifies regulators of cholesterol-modified hedgehog secretion in Drosophila.Endocytosis is required for Toll signaling and shaping of the Dorsal/NF-kappaB morphogen gradient during Drosophila embryogenesis.Cholesterol modification restricts the spread of Shh gradient in the limb bud.The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover.Regulation of smoothened by Drosophila G-protein-coupled receptor kinases.Steady-state invariant genetics: probing the role of morphogen gradient dynamics in developmental patterningThe extracellular loops of Smoothened play a regulatory role in control of Hedgehog pathway activation.Dependence receptors: mechanisms of an announced death.A Functional and Putative Physiological Role of Calcitriol in Patched1/Smoothened Interaction.Intracellular trafficking in Drosophila visual system development: a basis for pattern formation through simple mechanisms.Regulation of Hedgehog signaling by ubiquitination.The Drosophila WIF1 homolog Shifted maintains glypican-independent Hedgehog signaling and interacts with the Hedgehog co-receptors Ihog and Boi.Patched, the receptor of Hedgehog, is a lipoprotein receptor.Sequential phosphorylation of smoothened transduces graded hedgehog signaling.Lipid modification of secreted signaling proteins.Sonic Hedgehog Signaling and VACTERL Association.Diet controls Drosophila follicle stem cell proliferation via Hedgehog sequestration and releaseThe role of ciliary trafficking in Hedgehog receptor signaling.Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration.The hedgehog pathway gene shifted functions together with the hmgcr-dependent isoprenoid biosynthetic pathway to orchestrate germ cell migrationMechanism of inhibition of the tumor suppressor Patched by Sonic Hedgehog.Shaping morphogen gradients by proteoglycansThe extracellular regulation of bone morphogenetic protein signaling.Ubpy controls the stability of the ESCRT-0 subunit Hrs in development.Brain regionalization: of signaling centers and boundaries.Hedgehog and Notch signaling in enteric nervous system development.
P2860
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P2860
Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction.
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
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2004年论文
@wuu
name
Patched controls the Hedgehog ...... r role in signal transduction.
@ast
Patched controls the Hedgehog ...... r role in signal transduction.
@en
Patched controls the Hedgehog ...... r role in signal transduction.
@nl
type
label
Patched controls the Hedgehog ...... r role in signal transduction.
@ast
Patched controls the Hedgehog ...... r role in signal transduction.
@en
Patched controls the Hedgehog ...... r role in signal transduction.
@nl
prefLabel
Patched controls the Hedgehog ...... r role in signal transduction.
@ast
Patched controls the Hedgehog ...... r role in signal transduction.
@en
Patched controls the Hedgehog ...... r role in signal transduction.
@nl
P356
P1433
P1476
Patched controls the Hedgehog ...... r role in signal transduction.
@en
P2093
Isabel Guerrero
P304
P356
10.1242/DEV.01102
P407
P577
2004-04-21T00:00:00Z