Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.
about
Common and unique features of viral RNA-dependent polymerasesMechanistic differences in RNA-dependent DNA polymerization and fidelity between murine leukemia virus and HIV-1 reverse transcriptasesDNA replication error-induced extinction of diploid yeastBiochemical characterization of enzyme fidelity of influenza A virus RNA polymerase complexSequences in the 5' and 3' R elements of human immunodeficiency virus type 1 critical for efficient reverse transcriptionNormally lethal amino acid substitutions suppress an ultramutator DNA Polymerase δ variantImpact of sugar pucker on base pair and mispair stability.Human immunodeficiency virus type 1 DNA sequences genetically damaged by hypermutation are often abundant in patient peripheral blood mononuclear cells and may be generated during near-simultaneous infection and activation of CD4(+) T cells.Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors.Probing the active site steric flexibility of HIV-1 reverse transcriptase: different constraints for DNA- versus RNA-templated synthesis.Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type-1 integrase.Mutagenicity and pausing of HIV reverse transcriptase during HIV plus-strand DNA synthesisMarked infidelity of human immunodeficiency virus type 1 reverse transcriptase at RNA and DNA template endsInhibitors of HIV-1 reverse transcriptase and fidelity of in vitro DNA replication.Reverse transcriptase--a general discussion.dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants.High rate of mismatch extension during reverse transcription in a single round of retrovirus replicationHuman immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesisLys66 residue as a determinant of high mismatch extension and misinsertion rates of HIV-1 reverse transcriptase.Genetic elements of plant viruses as tools for genetic engineering.A DNA polymerase alpha pause site is a hot spot for nucleotide misinsertionUnequal human immunodeficiency virus type 1 reverse transcriptase error rates with RNA and DNA templates.Analysis of HIV-1 intersubtype recombination breakpoints suggests region with high pairing probability may be a more fundamental factor than sequence similarity affecting HIV-1 recombinationThe remarkable frequency of human immunodeficiency virus type 1 genetic recombinationError-prone retrotransposition: rime of the ancient mutators.Replication infidelity during a single cycle of Ty1 retrotransposition.Mutation rates and intrinsic fidelity of retroviral reverse transcriptases.The E249K mutator mutant of DNA polymerase beta extends mispaired termini.Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase.Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase.K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies.Dynamical properties and thresholds of an HIV model with super-infection.Replication errors during in vivo Ty1 transposition are linked to heterogeneous RNase H cleavage sites.Effects of limiting homology at the site of intermolecular recombinogenic template switching during Moloney murine leukemia virus replicationIn vitro expansion of GGC:GCC repeats: identification of the preferred strand of expansion.Strand transfer is enhanced by mismatched nucleotides at the 3' primer terminus: a possible link between HIV reverse transcriptase fidelity and recombination.Mispair extension fidelity of human immunodeficiency virus type 1 reverse transcriptases with amino acid substitutions affecting Tyr115.Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase.Increased polymerase fidelity of E89G, a nucleoside analog-resistant variant of human immunodeficiency virus type 1 reverse transcriptase.Efficient extension of a misaligned tRNA-primer during replication of the HIV-1 retrovirus.
P2860
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P2860
Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.
description
1989 nî lūn-bûn
@nan
1989 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Extension of mismatched 3' ter ...... type 1 reverse transcriptase.
@ast
Extension of mismatched 3' ter ...... type 1 reverse transcriptase.
@en
Extension of mismatched 3' ter ...... type 1 reverse transcriptase.
@nl
type
label
Extension of mismatched 3' ter ...... type 1 reverse transcriptase.
@ast
Extension of mismatched 3' ter ...... type 1 reverse transcriptase.
@en
Extension of mismatched 3' ter ...... type 1 reverse transcriptase.
@nl
prefLabel
Extension of mismatched 3' ter ...... type 1 reverse transcriptase.
@ast
Extension of mismatched 3' ter ...... type 1 reverse transcriptase.
@en
Extension of mismatched 3' ter ...... type 1 reverse transcriptase.
@nl
P2093
P2860
P356
P1476
Extension of mismatched 3' ter ...... s type 1 reverse transcriptase
@en
P2093
B D Preston
F W Perrino
P2860
P304
P356
10.1073/PNAS.86.21.8343
P407
P577
1989-11-01T00:00:00Z