Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering.
about
Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathwayCoat/Tether Interactions-Exception or Rule?Vps1 in the late endosome-to-vacuole traffic.Distinct palmitoylation events at the amino-terminal conserved cysteines of Env7 direct its stability, localization, and vacuolar fusion regulation in S. cerevisiaeAn overexpression screen in Saccharomyces cerevisiae identifies novel genes that affect endocytic protein trafficking.Functional separation of endosomal fusion factors and the class C core vacuole/endosome tethering (CORVET) complex in endosome biogenesisThe HOPS/Class C Vps Complex Tethers High-Curvature Membranes via a Direct Protein-Membrane Interaction.The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes.The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3.Comparative genomic analysis of multi-subunit tethering complexes demonstrates an ancient pan-eukaryotic complement and sculpting in ApicomplexaNew organelles by gene duplication in a biophysical model of eukaryote endomembrane evolutionThe HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane.The yeast vacuolar Rab GTPase Ypt7p has an activity beyond membrane recruitment of the homotypic fusion and protein sorting-Class C Vps complexMolecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex.Endosomal maturation by Rab conversion in Aspergillus nidulans is coupled to dynein-mediated basipetal movementHow and why intralumenal membrane fragments form during vacuolar lysosome fusion.Dynamic association of the PI3P-interacting Mon1-Ccz1 GEF with vacuoles is controlled through its phosphorylation by the type 1 casein kinase Yck3.Characterization of TSET, an ancient and widespread membrane trafficking complex.Adaptor protein complexes and intracellular transport.Evolution: On a bender--BARs, ESCRTs, COPs, and finally getting your coatTracking of the dynamic localization of the Rab-specific HOPS subunits reveal their distinct interaction with Ypt7 and vacuoles.Amphipathic lipid packing sensor motifs: probing bilayer defects with hydrophobic residuesThe N-terminal domains of Vps3 and Vps8 are critical for localization and function of the CORVET tethering complex on endosomes.Yeast vacuolar HOPS, regulated by its kinase, exploits affinities for acidic lipids and Rab:GTP for membrane binding and to catalyze tethering and fusion.Metazoan cell biology of the HOPS tethering complexThe yeast Batten disease orthologue Btn1 controls endosome-Golgi retrograde transport via SNARE assembly.Identification of a Rab GTPase-activating protein cascade that controls recycling of the Rab5 GTPase Vps21 from the vacuole.Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.The casein kinases Yck1p and Yck2p act in the secretory pathway, in part, by regulating the Rab exchange factor Sec2p.The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes.Phosphorylation of the Rab exchange factor Sec2p directs a switch in regulatory binding partners.Vacuolar protein sorting mechanisms in apicomplexan parasitesCaenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1.Tethering complexes in the endocytic pathway: CORVET and HOPS.Functional homologies in vesicle tethering.Deleting the DAG kinase Dgk1 augments yeast vacuole fusion through increased Ypt7 activity and altered membrane fluidity.Multivalent Rab interactions determine tether-mediated membrane fusion.Electron microscopy for ultrastructural analysis and protein localization in Saccharomyces cerevisiae.The Dsl1 protein tethering complex is a resident endoplasmic reticulum complex, which interacts with five soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptors (SNAREs): implications for fusion and fusion regulation.Saccharomyces cerevisiae Env7 is a novel serine/threonine kinase 16-related protein kinase and negatively regulates organelle fusion at the lysosomal vacuole.
P2860
Q24339502-5A29A938-BD13-401B-8358-00F9EF50B74EQ26744484-902663EC-B26D-4E43-82E5-A02980991824Q27930436-A81D3C57-EB8F-4D09-B4ED-B82E648DB8F2Q27931899-7805FAA3-2C05-4BE9-9363-E1DA2665C3F5Q27932503-4CCAF856-0154-4FE1-91C5-0D611FDA7614Q27937073-835C572C-0E34-4DD4-90DD-050A6AADF675Q27937119-3E7AD8B5-4485-49FC-998B-19257640B03FQ27939522-E4ADC513-2048-4DF1-9548-135CCC2880EDQ27940067-01B69408-1459-4B7A-8730-C1E9C563243FQ27974681-FF11BD35-5AFC-49E7-B178-A6E46817C1D9Q28681946-866F15A6-9E73-42C3-9E78-C22979766951Q30299905-18F5CACE-6410-4E16-905B-96E0AB0EA4FCQ30415875-B7BACC39-209E-4727-96E1-A1CAB54708C5Q30505172-A88B4AC3-14B4-43E9-BA6A-4D1C5635B721Q30514033-5D6CD052-0FB1-4DBE-A336-6817E9548B90Q30834820-88967163-4287-4D5E-AE26-482FD3322B66Q33604383-A6FAB1B3-D8F2-462E-8D35-00EB61A75275Q33653804-8336740B-45AB-4575-9275-A041A9EDD166Q33964846-03C20C3D-D0C0-4962-B16C-07658936FB26Q34027290-C4C199AA-B470-411F-9951-5931164EC653Q34142922-CF5A33FE-9B7E-4F46-8EAD-A166A3FEA058Q34329941-289FCDE7-7CFA-4495-AB88-143715AC95DBQ34807013-A2A5CCCB-2C05-4993-BADA-7727CE7274E6Q34960727-99085096-A319-465D-91C1-9C10407FDC3AQ35214573-483DDB1D-2EC9-4135-A677-72DFC29D6350Q35406449-561B7B12-F86F-4793-AB50-4CB5911DCBC0Q36063687-D111934B-71BD-47AA-ABEB-3E62CFC72B13Q36381900-AB5912FC-259A-4C6D-9BE3-0DB47B9B53DEQ36572687-E1036FF2-03A2-4C54-9834-FBFF5FC762D2Q36673162-9155C93D-3BCE-4662-9810-58A1B22FC8D3Q37394960-1018E4F0-6F18-4841-9E94-317A84C6C460Q37499182-C7B3EE3A-042C-4491-9328-BC83BBC3B248Q37669229-472355CE-6879-461E-81C5-C3B66369DB96Q38076778-44D3F902-6F0D-488D-8ECE-7F4BF3B2E0BCQ38527249-A9CB2614-23ED-40CC-8876-49E7DB171E0FQ38919003-568B3C91-04FF-4C05-9234-755712152BF6Q39182367-9AFBA458-9DE5-4F94-8807-A8EF7254591EQ39208061-81D32C7D-C0AD-4AAB-A898-0AF5527DAB3DQ41897201-13460BCA-8E9F-43E2-8305-F459D246DB2DQ42059939-70A97917-1E91-431F-BA0F-1EC3B83AA04D
P2860
Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Phosphorylation of a membrane ...... t Vps41 in membrane tethering.
@ast
Phosphorylation of a membrane ...... t Vps41 in membrane tethering.
@en
Phosphorylation of a membrane ...... t Vps41 in membrane tethering.
@nl
type
label
Phosphorylation of a membrane ...... t Vps41 in membrane tethering.
@ast
Phosphorylation of a membrane ...... t Vps41 in membrane tethering.
@en
Phosphorylation of a membrane ...... t Vps41 in membrane tethering.
@nl
prefLabel
Phosphorylation of a membrane ...... t Vps41 in membrane tethering.
@ast
Phosphorylation of a membrane ...... t Vps41 in membrane tethering.
@en
Phosphorylation of a membrane ...... t Vps41 in membrane tethering.
@nl
P2093
P2860
P50
P356
P1476
Phosphorylation of a membrane ...... it Vps41 in membrane tethering
@en
P2093
Angela Perz
Christian Ungermann
Cornelia Bröcker
Ioan Orban
Janice Griffith
Lars Langemeyer
Muriel Mari
Ralf Rethmeier
Siegfried Engelbrecht-Vandré
P2860
P304
P356
10.1083/JCB.201004092
P407
P577
2010-11-01T00:00:00Z