Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. - Wikidata - awgldk - TriplyDB

Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering.

Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering.

http://www.wikidata.org/entity/Q34317009

about

Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway Coat/Tether Interactions-Exception or Rule?Vps1 in the late endosome-to-vacuole traffic.Distinct palmitoylation events at the amino-terminal conserved cysteines of Env7 direct its stability, localization, and vacuolar fusion regulation in S. cerevisiae An overexpression screen in Saccharomyces cerevisiae identifies novel genes that affect endocytic protein trafficking.Functional separation of endosomal fusion factors and the class C core vacuole/endosome tethering (CORVET) complex in endosome biogenesis The HOPS/Class C Vps Complex Tethers High-Curvature Membranes via a Direct Protein-Membrane Interaction.The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes.The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3.Comparative genomic analysis of multi-subunit tethering complexes demonstrates an ancient pan-eukaryotic complement and sculpting in Apicomplexa New organelles by gene duplication in a biophysical model of eukaryote endomembrane evolution The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane.The yeast vacuolar Rab GTPase Ypt7p has an activity beyond membrane recruitment of the homotypic fusion and protein sorting-Class C Vps complex Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex.Endosomal maturation by Rab conversion in Aspergillus nidulans is coupled to dynein-mediated basipetal movement How and why intralumenal membrane fragments form during vacuolar lysosome fusion.Dynamic association of the PI3P-interacting Mon1-Ccz1 GEF with vacuoles is controlled through its phosphorylation by the type 1 casein kinase Yck3.Characterization of TSET, an ancient and widespread membrane trafficking complex.Adaptor protein complexes and intracellular transport.Evolution: On a bender--BARs, ESCRTs, COPs, and finally getting your coat Tracking of the dynamic localization of the Rab-specific HOPS subunits reveal their distinct interaction with Ypt7 and vacuoles.Amphipathic lipid packing sensor motifs: probing bilayer defects with hydrophobic residues The N-terminal domains of Vps3 and Vps8 are critical for localization and function of the CORVET tethering complex on endosomes.Yeast vacuolar HOPS, regulated by its kinase, exploits affinities for acidic lipids and Rab:GTP for membrane binding and to catalyze tethering and fusion.Metazoan cell biology of the HOPS tethering complex The yeast Batten disease orthologue Btn1 controls endosome-Golgi retrograde transport via SNARE assembly.Identification of a Rab GTPase-activating protein cascade that controls recycling of the Rab5 GTPase Vps21 from the vacuole.Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.The casein kinases Yck1p and Yck2p act in the secretory pathway, in part, by regulating the Rab exchange factor Sec2p.The CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranes.Phosphorylation of the Rab exchange factor Sec2p directs a switch in regulatory binding partners.Vacuolar protein sorting mechanisms in apicomplexan parasites Caenorhabditis elegans HOPS and CCZ-1 mediate trafficking to lysosome-related organelles independently of RAB-7 and SAND-1.Tethering complexes in the endocytic pathway: CORVET and HOPS.Functional homologies in vesicle tethering.Deleting the DAG kinase Dgk1 augments yeast vacuole fusion through increased Ypt7 activity and altered membrane fluidity.Multivalent Rab interactions determine tether-mediated membrane fusion.Electron microscopy for ultrastructural analysis and protein localization in Saccharomyces cerevisiae.The Dsl1 protein tethering complex is a resident endoplasmic reticulum complex, which interacts with five soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptors (SNAREs): implications for fusion and fusion regulation.Saccharomyces cerevisiae Env7 is a novel serine/threonine kinase 16-related protein kinase and negatively regulates organelle fusion at the lysosomal vacuole.

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P2860

Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering.

http://www.wikidata.org/entity/Q34317009

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Phosphorylation of a membrane ...... t Vps41 in membrane tethering.

@ast

Phosphorylation of a membrane ...... t Vps41 in membrane tethering.

@en

Phosphorylation of a membrane ...... t Vps41 in membrane tethering.

@nl

type

label

Phosphorylation of a membrane ...... t Vps41 in membrane tethering.

@ast

Phosphorylation of a membrane ...... t Vps41 in membrane tethering.

@en

Phosphorylation of a membrane ...... t Vps41 in membrane tethering.

@nl

prefLabel

Phosphorylation of a membrane ...... t Vps41 in membrane tethering.

@ast

Phosphorylation of a membrane ...... t Vps41 in membrane tethering.

@en

Phosphorylation of a membrane ...... t Vps41 in membrane tethering.

@nl

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P1433

Journal of Cell Biology

P1476

Phosphorylation of a membrane ...... it Vps41 in membrane tethering

@en

P2093

Angela Perz

http://www.w3.org/2001/XMLSchema#string

Christian Ungermann

http://www.w3.org/2001/XMLSchema#string

Cornelia Bröcker

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Ioan Orban

http://www.w3.org/2001/XMLSchema#string

Janice Griffith

http://www.w3.org/2001/XMLSchema#string

Lars Langemeyer

http://www.w3.org/2001/XMLSchema#string

Muriel Mari

http://www.w3.org/2001/XMLSchema#string

Ralf Rethmeier

http://www.w3.org/2001/XMLSchema#string

Siegfried Engelbrecht-Vandré

http://www.w3.org/2001/XMLSchema#string

P2860

hVPS41 is expressed in multiple isoforms and can associate with vesicles through a RING-H2 finger motif

Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function

Identification of the switch in early-to-late endosome transition

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system.

The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae

The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole.

The Mon1-Ccz1 complex is the GEF of the late endosomal Rab7 homolog Ypt7.

Defined subunit arrangement and rab interactions are required for functionality of the HOPS tethering complex.

Formation of AP-3 transport intermediates requires Vps41 function.

P304

845-859

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scholarly article

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10.1083/JCB.201004092

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P433

4

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191

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Fulvio Reggiori

Margarita Cabrera

Heinz-Jürgen Steinhoff

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2010-11-01T00:00:00Z

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47794580

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21079247

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P921

phosphorylation

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2983053

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