Type 10 soluble adenylyl cyclase is overexpressed in prostate carcinoma and controls proliferation of prostate cancer cells
about
Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonateThe cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cellsIntegration of somatic mutation, expression and functional data reveals potential driver genes predictive of breast cancer survival.The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention.Different cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling.Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein.Established and potential physiological roles of bicarbonate-sensing soluble adenylyl cyclase (sAC) in aquatic animals.Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets.The activity of cAMP-phosphodiesterase 4D7 (PDE4D7) is regulated by protein kinase A-dependent phosphorylation within its unique N-terminus.Cyclase-Associated Protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.Soluble adenylyl cyclase: A novel player in cardiac hypertrophy induced by isoprenaline or pressure overload.Functional Significance of the Adcy10-Dependent Intracellular cAMP Compartments.
P2860
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P2860
Type 10 soluble adenylyl cyclase is overexpressed in prostate carcinoma and controls proliferation of prostate cancer cells
description
2012 nî lūn-bûn
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2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
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2012年論文
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2012年论文
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name
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@ast
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@en
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@nl
type
label
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@ast
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@en
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@nl
prefLabel
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@ast
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@en
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@nl
P2093
P2860
P356
P1476
Type 10 soluble adenylyl cycla ...... ation of prostate cancer cells
@en
P2093
Avinash Appukuttan
Brian D Robinson
H Peter Reusch
Hanna Flacke
Jan-Paul Flacke
Joachim Noldus
Jonathan H Zippin
Rein-Jüri Palisaar
Yury Ladilov
P2860
P304
P356
10.1074/JBC.M112.403279
P407
P577
2012-12-19T00:00:00Z