Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172.
about
The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependentThe endocannabinoid system as a target for the treatment of cannabis dependenceThe endocannabinoid system as an emerging target of pharmacotherapyIdentification of intracellular carriers for the endocannabinoid anandamideChemical probes of endocannabinoid metabolismTRPV1 in brain is involved in acetaminophen-induced antinociceptionExploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporterConversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous systemN-arachidonoyl-dopamine tunes synaptic transmission onto dopaminergic neurons by activating both cannabinoid and vanilloid receptorsIdentification of a high-affinity binding site involved in the transport of endocannabinoids.Enzymatic pathways that regulate endocannabinoid signaling in the nervous systemFatty acid amide hydrolase-dependent generation of antinociceptive drug metabolites acting on TRPV1 in the brainPharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus.In vivo pharmacology of endocannabinoids and their metabolic inhibitors: therapeutic implications in Parkinson's disease and abuse liability2012 Division of medicinal chemistry award address. Trekking the cannabinoid road: a personal perspectivePitfalls and solutions in assaying anandamide transport in cellsEnhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modalityRegulation of gonadotropin-releasing hormone secretion by cannabinoids.The endocannabinoid system as a target for the treatment of neurodegenerative disease.The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development.The role of endocannabinoids in pain modulation.Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effectsAnandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase.Endocannabinoids: getting the message across.Role of endocannabinoids and cannabinoid-1 receptors in cerebrocortical blood flow regulation.Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake.TRPV1 mediates cellular uptake of anandamide and thus promotes endothelial cell proliferation and network-formation.Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown.New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosisInvolvement of fatty acid amide hydrolase and fatty acid binding protein 5 in the uptake of anandamide by cell lines with different levels of fatty acid amide hydrolase expression: a pharmacological study.Role of the endogenous cannabinoid system in nicotine addiction: novel insights.Hydrogen-bonded His93 as a sensitive probe for identifying inhibitors of the endocannabinoid transport protein FABP7.Molecular composition of the endocannabinoid system at glutamatergic synapses.Cannabinoids, electrophysiology, and retrograde messengers: challenges for the next 5 yearsFatty acid-binding proteins transport N-acylethanolamines to nuclear receptors and are targets of endocannabinoid transport inhibitors.A role for the anandamide membrane transporter in TRPV1-mediated neurosecretion from trigeminal sensory neurons.The endocannabinoid system: physiology and pharmacology.Effects of alterations in cannabinoid signaling, alone and in combination with morphine, on pain-elicited and pain-suppressed behavior in mice.New insights on endocannabinoid transmission in psychomotor disorders.
P2860
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P2860
Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@ast
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@en
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@nl
type
label
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@ast
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@en
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@nl
prefLabel
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@ast
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@en
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@nl
P2093
P2860
P921
P356
P1476
Anandamide transport is indepe ...... is-resistant inhibitor AM1172.
@en
P2093
P2860
P304
P356
10.1073/PNAS.0400997101
P407
P577
2004-05-11T00:00:00Z