Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system
about
Role of cues and contexts on drug-seeking behaviourMultiple roles for orexin/hypocretin in addictionA novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in ratsIdentification of neuropeptide receptors expressed by melanin-concentrating hormone neurons.A critical role of lateral hypothalamus in context-induced relapse to alcohol seeking after punishment-imposed abstinence.Anti-aggressive effects of neuropeptide S independent of anxiolysis in male rats.Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluation.Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).Effects of the neuropeptide S receptor antagonist RTI-118 on abuse-related facilitation of intracranial self-stimulation produced by cocaine and methylenedioxypyrovalerone (MDPV) in rats.Neuropeptide S facilitates mice olfactory function through activation of cognate receptor-expressing neurons in the olfactory cortex.Intraventricular administration of neuropeptide S has reward-like effects.Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68).Antagonism of the neuropeptide S receptor with RTI-118 decreases cocaine self-administration and cocaine-seeking behavior in rats.Stress-related neuropeptides and addictive behaviors: beyond the usual suspects.Translational approach to develop novel medications on alcohol addiction: focus on neuropeptides.The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research.Emerging targets for addiction neuropharmacology: From mechanisms to therapeuticsNeuropeptide S receptor: recent updates on nonpeptide antagonist discovery.Psychiatric disturbances regulate the innate immune system in CSF of conscious mice.Identification of the first biased NPS receptor agonist that retains anxiolytic and memory promoting effects with reduced levels of locomotor stimulation.Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner.Role of perineuronal nets in the anterior dorsal lateral hypothalamic area in the acquisition of cocaine-induced conditioned place preference and self-administration.Neuropeptide S receptor ligands: a patent review (2005-2016).Neuropeptide systems and new treatments for nicotine addiction.Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction.Neuropeptide S differently modulates alcohol-related behaviors in alcohol-preferring and non-preferring rats.Neuropeptide S precursor knockout mice display memory and arousal deficits.A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?Neuropeptide-S evoked arousal with electroencephalogram slow-wave compensatory drive in rats.Hypothalamic neuropeptide S receptor blockade decreases discriminative cue-induced reinstatement of cocaine seeking in the rat.Neuropeptide S ameliorates olfactory spatial memory impairment induced by scopolamine and MK801 through activation of cognate receptor-expressing neurons in the subiculum complex.Anti-stress neuropharmacological mechanisms and targets for addiction treatment: A translational framework
P2860
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P2860
Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Neuropeptide S facilitates cue ...... hypothalamic hypocretin system
@en
Neuropeptide S facilitates cue ...... hypothalamic hypocretin system
@nl
type
label
Neuropeptide S facilitates cue ...... hypothalamic hypocretin system
@en
Neuropeptide S facilitates cue ...... hypothalamic hypocretin system
@nl
prefLabel
Neuropeptide S facilitates cue ...... hypothalamic hypocretin system
@en
Neuropeptide S facilitates cue ...... hypothalamic hypocretin system
@nl
P2093
P2860
P356
P1476
Neuropeptide S facilitates cue ...... hypothalamic hypocretin system
@en
P2093
Barbara Ruggeri
Daina Economidou
Friedbert Weiss
Juan Marugan
Luis de Lecea
Markus Heilig
Marsida Kallupi
Massimo Ubaldi
Maurizio Massi
Nazzareno Cannella
P2860
P304
19567-19572
P356
10.1073/PNAS.1004100107
P407
P577
2010-10-25T00:00:00Z