A simple stereocontrolled synthesis of salinosporamide A.
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Concise total synthesis of (+/-)-salinosporamide A, (+/-)-cinnabaramide A, and derivatives via a bis-cyclization process: implications for a biosynthetic pathway?Discovery and development of the anticancer agent salinosporamide A (NPI-0052).Marine Rare Actinobacteria: Isolation, Characterization, and Strategies for Harnessing Bioactive Compounds.Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamidesSalinosporamide natural products: Potent 20 S proteasome inhibitors as promising cancer chemotherapeutics.Sporolide B: Synthetic StudiesNitrenium ion azaspirocyclization-spirodienone cleavage: a new synthetic strategy for the stereocontrolled preparation of highly substituted lactams and N-hydroxy lactams.Computational design of enone-binding proteins with catalytic activity for the Morita-Baylis-Hillman reactionSynthesis of sultam scaffolds via intramolecular oxa-Michael and diastereoselective Baylis-Hillman reactions.Low temperature n-butyllithium-induced [3,3]-sigmatropic rearrangement/electrophile trapping reactions of allyl-1,1-dichlorovinyl ethers. Synthesis of β-, γ- and δ-lactones.Employing homoenolates generated by NHC catalysis in carbon-carbon bond-forming reactions: state of the art.Synthesis and pharmacology of proteasome inhibitors.Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products.Synthetic approaches towards alkaloids bearing α-tertiary amines.Recent advances in the Overman rearrangement: synthesis of natural products and valuable compounds.Construction of Polycyclic γ-Lactams and Related Heterocycles via Electron Catalysis.Catalytic Asymmetric Synthesis of Ketene Heterodimer β-Lactones: Scope and Limitations.Bioinspired total synthesis and human proteasome inhibitory activity of (-)-salinosporamide A, (-)-homosalinosporamide A, and derivatives obtained via organonucleophile promoted bis-cyclizations.(S)-4-Trimethylsilyl-3-butyn-2-ol as an auxiliary for stereocontrolled synthesis of salinosporamide analogs with modifications at positions C2 and C5.A(1,3)-strain enabled retention of chirality during bis-cyclization of beta-ketoamides: total synthesis of (-)-salinosporamide A and (-)-homosalinosporamide A.Formal synthesis of salinosporamide A via NHC-catalyzed intramolecular lactonizationMorita-Baylis-Hillman reaction of acrylamide with isatin derivatives.Developing a new resource for drug discovery: marine actinomycete bacteria.Entry to heterocycles based on indium-catalyzed conia-ene reactions: asymmetric synthesis of (-)-salinosporamide A.An enantioselective organocatalytic intramolecular Morita-Baylis-Hillman (IMBH) reaction of dienones, and elaboration of the IMBH adducts to fluorenones.Enantioselective synthesis of α-benzylated lanthionines and related tripeptides for biological incorporation into E. coli peptidoglycan.Synthesis and bioactivity of fused- and spiro-β-lactone-lactam systems.
P2860
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P2860
A simple stereocontrolled synthesis of salinosporamide A.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A simple stereocontrolled synthesis of salinosporamide A.
@ast
A simple stereocontrolled synthesis of salinosporamide A.
@en
A simple stereocontrolled synthesis of salinosporamide A.
@nl
type
label
A simple stereocontrolled synthesis of salinosporamide A.
@ast
A simple stereocontrolled synthesis of salinosporamide A.
@en
A simple stereocontrolled synthesis of salinosporamide A.
@nl
prefLabel
A simple stereocontrolled synthesis of salinosporamide A.
@ast
A simple stereocontrolled synthesis of salinosporamide A.
@en
A simple stereocontrolled synthesis of salinosporamide A.
@nl
P2093
P356
P1476
A simple stereocontrolled synthesis of salinosporamide A.
@en
P2093
Leleti Rajender Reddy
P Saravanan
P304
P356
10.1021/JA048613P
P407
P577
2004-05-01T00:00:00Z