Echinomycin-induced hypersensitivity to osmium tetroxide of DNA fragments incapable of forming Hoogsteen base pairs
about
The multiple personalities of Watson and Crick strandsSite-specific intercalation at the triplex-duplex junction induces a conformational change which is detectable by hypersensitivity to diethylpyrocarbonate.A historical account of Hoogsteen base-pairs in duplex DNA.Local supercoil-stabilized DNA structures.Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies.Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: effect of metal cis/trans isomerism and DNA threading groups.Binding of echinomycin to d(GCGC)2 and d(CCGG)2: distinct stacking interactions dictate the sequence-dependent formation of Hoogsteen base pairs.Proton NMR study of the [d(ACGTATACGT)]2-2echinomycin complex: conformational changes between echinomycin binding sites.The 2-amino group of guanine is absolutely required for specific binding of the anti-cancer antibiotic echinomycin to DNA.Localized chemical reactivity in DNA associated with the sequence-specific bisintercalation of echinomycin.
P2860
Q21203763-A8D988C9-0C6D-482D-9FBE-A4573CFF7F65Q33360828-E4E5FAFC-B35C-4BD6-945E-30BD6102A3C6Q34354855-EDC25971-C5E1-41D2-86D2-7AEE5E822D60Q34922005-B35FAA43-D105-46AD-8827-9DD697DBBA10Q36724710-8508B755-C74A-4AD1-AF42-9E0B0E5ABDE4Q37230414-066F6C97-AF60-4BD0-A642-B71FD4ABBFA8Q38305966-3D80DC39-CF80-4390-9E6F-985CEF2989EDQ38328640-748C7CC8-371D-450B-BC51-F7A419A85531Q40535130-4D116D01-FD90-466B-9C56-58DEB98C5FCEQ42274046-5986CE89-8A33-4598-A910-D3046748F2D3
P2860
Echinomycin-induced hypersensitivity to osmium tetroxide of DNA fragments incapable of forming Hoogsteen base pairs
description
1989 nî lūn-bûn
@nan
1989 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@ast
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@en
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@nl
type
label
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@ast
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@en
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@nl
prefLabel
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@ast
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@en
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@nl
P2093
P2860
P356
P1476
Echinomycin-induced hypersensi ...... f forming Hoogsteen base pairs
@en
P2093
P2860
P304
P356
10.1073/PNAS.86.24.9687
P407
P577
1989-12-01T00:00:00Z