SDF-1 inhibition targets the bone marrow niche for cancer therapy.
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Signaling Interplay between Bone Marrow Adipose Tissue and Multiple Myeloma cellsThe miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1.Soluble Factors on Stage to Direct Mesenchymal Stem Cells Fate.The notorious R.N.A. in the spotlight - drug or target for the treatment of diseaseThe importance of the genomic landscape in Waldenström's Macroglobulinemia for targeted therapeutical interventions.Pathogenesis beyond the cancer clone(s) in multiple myeloma.SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction.Dynamic interplay between bone and multiple myeloma: emerging roles of the osteoblastMist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche.Navigating the bone marrow niche: translational insights and cancer-driven dysfunction.CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation.CCR10/CCL27 crosstalk contributes to failure of proteasome-inhibitors in multiple myeloma.CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks.Adipocyte-Lineage Cells Support Growth and Dissemination of Multiple Myeloma in Bone.Adipose, Bone, and Myeloma: Contributions from the Microenvironment.Microenvironment drug resistance in multiple myeloma: emerging new players.Targeting the Bone Marrow Microenvironment.MGUS to myeloma: a mysterious gammopathy of underexplored significance.Mechanisms of Resistance in Multiple Myeloma.Olaptesed pegol, an anti-CXCL12/SDF-1 Spiegelmer, alone and with bortezomib-dexamethasone in relapsed/refractory multiple myeloma: a Phase IIa Study.Newly established myeloma-derived stromal cell line MSP-1 supports multiple myeloma proliferation, migration, and adhesion and induces drug resistance more than normal-derived stroma.Promising therapies in multiple myeloma.Inhibition of SDF-1-induced migration of oncogene-driven myeloid leukemia by the L-RNA aptamer (Spiegelmer), NOX-A12, and potentiation of tyrosine kinase inhibition.Dynamic cellular phynotyping defines specific mobilization mechanisms of human hematopoietic stem and progenitor cells induced by SDF1α versus synthetic agents.CXCL12 and CXCR7 are relevant targets to reverse cell adhesion-mediated drug resistance in multiple myeloma.The bone-marrow niche in MDS and MGUS: implications for AML and MM.Aptamer Therapeutics in Cancer: Current and Future.The bone marrow metastasis niche in retinoblastoma.Role of Tumor-Derived Chemokines in Osteolytic Bone Metastasis.The NF-κB Activating Pathways in Multiple Myeloma.
P2860
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P2860
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@ast
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@en
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@nl
type
label
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@ast
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@en
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@nl
prefLabel
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@ast
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@en
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@nl
P2093
P2860
P50
P1433
P1476
SDF-1 inhibition targets the bone marrow niche for cancer therapy.
@en
P2093
Anna Kruschinski
Christian Maasch
Dirk Eulberg
Dirk Zboralski
Irene M Ghobrial
Klaus Buchner
Marco Ungari
Michele Moschetta
Silvia Lonardi
Stefan Vonhoff
P2860
P304
P356
10.1016/J.CELREP.2014.08.042
P50
P577
2014-09-25T00:00:00Z