Spindle checkpoint protein dynamics at kinetochores in living cells.
about
Bub3 is a spindle assembly checkpoint protein regulating chromosome segregation during mouse oocyte meiosisReverse engineering of the spindle assembly checkpointLoss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosisThe functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosisThe DYNLT3 light chain directly links cytoplasmic dynein to a spindle checkpoint protein, Bub3ZW10 links mitotic checkpoint signaling to the structural kinetochore.Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death.Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interactionCAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment.The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachments.Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpointBub1 regulates chromosome segregation in a kinetochore-independent mannerA microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targetingBuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignmentCentrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylationRab11 endosomes contribute to mitotic spindle organization and orientationHec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.Linking kinetochore-microtubule binding to the spindle checkpointStable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpointThe APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.The Nup107-160 nucleoporin complex is required for correct bipolar spindle assemblyStructural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template modelThe multifaceted roles of the HORMA domain in cellular signalingFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisKNL1: bringing order to the kinetochoreKinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint responseARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochoresThe multiple roles of mps1 in Drosophila female meiosisDynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly CheckpointHypoxia transiently sequesters mps1 and polo to collagenase-sensitive filaments in Drosophila prometaphase oocytesDynein/Dynactin-mediated transport of kinetochore components off kinetochores and onto spindle poles induced by nordihydroguaiaretic acidDefining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 InhibitionSmall-molecule kinase inhibitors provide insight into Mps1 cell cycle functionBub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signalingMad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint.Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae.Bir1 deletion causes malfunction of the spindle assembly checkpoint and apoptosis in yeastDual mechanisms regulate the recruitment of spindle assembly checkpoint proteins to the budding yeast kinetochore
P2860
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P2860
Spindle checkpoint protein dynamics at kinetochores in living cells.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Spindle checkpoint protein dynamics at kinetochores in living cells.
@ast
Spindle checkpoint protein dynamics at kinetochores in living cells.
@en
Spindle checkpoint protein dynamics at kinetochores in living cells.
@nl
type
label
Spindle checkpoint protein dynamics at kinetochores in living cells.
@ast
Spindle checkpoint protein dynamics at kinetochores in living cells.
@en
Spindle checkpoint protein dynamics at kinetochores in living cells.
@nl
prefLabel
Spindle checkpoint protein dynamics at kinetochores in living cells.
@ast
Spindle checkpoint protein dynamics at kinetochores in living cells.
@en
Spindle checkpoint protein dynamics at kinetochores in living cells.
@nl
P2093
P1433
P1476
Spindle checkpoint protein dynamics at kinetochores in living cells
@en
P2093
Bonnie J Howell
E D Salmon
Emily M Farrar
Guowei Fang
Scott Stewart
P304
P356
10.1016/J.CUB.2004.05.053
P407
P50
P577
2004-06-01T00:00:00Z