High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria. - Wikidata - awgldk - TriplyDB

High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria.

High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria.

http://www.wikidata.org/entity/Q34326742

about

Antigen reversal identifies targets of opsonizing IgGs against pregnancy-associated malaria Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates.Bacterial superglue enables easy development of efficient virus-like particle based vaccines.Lack of avidity maturation of merozoite antigen-specific antibodies with increasing exposure to Plasmodium falciparum amongst children and adults exposed to endemic malaria in Kenya.The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site Parity-dependent recognition of DBL1X-3X suggests an important role of the VAR2CSA high-affinity CSA-binding region in the development of the humoral response against placental malaria.Malaria and immunity during pregnancy and postpartum: a tale of two species CD14(hi)CD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so Malaria during Pregnancy.Comparison of the specificity of antibodies to VAR2CSA in Cameroonian multigravidae with and without placental malaria: a retrospective case-control study.Influence of Intermittent Preventive Treatment on Antibodies to VAR2CSA in Pregnant Cameroonian Women Malaria risk factors in women on intermittent preventive treatment at delivery and their effects on pregnancy outcome in Sanaga-Maritime, Cameroon.Murine Model for Preclinical Studies of Var2CSA-Mediated Pathology Associated with Malaria in Pregnancy Development of severe pathology in immunized pregnant mice challenged with lethal malaria parasites Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers.Association between malaria immunity and pregnancy outcomes among Malawian pregnant women receiving nutrient supplementation.Usefulness of a biomarker to identify placental dysfunction in the context of malaria Individuals living in a malaria-endemic area of Cameroon do not have an acquired antibody response to Plasmodium falciparum histidine-rich protein 2.Avidity of anti-malarial antibodies inversely related to transmission intensity at three sites in Uganda.Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain Increased risk of low birth weight in women with placental malaria associated with P. falciparum VAR2CSA clade.A new method for sequencing the hypervariable Plasmodium falciparum gene var2csa from clinical samples.Statistical prediction of immunity to placental malaria based on multi-assay antibody data for malarial antigens.Plasmodium falciparum infection early in pregnancy has profound consequences for foetal growth.Assessment of the quality and quantity of naturally induced antibody responses to EBA175RIII-V in Ghanaian children living in two communities with varying malaria transmission patterns.Increased Susceptibility to Plasmodium falciparum in Infants is associated with Low, not High, Placental Malaria Parasitemia.Antibody levels to recombinant VAR2CSA domains vary with Plasmodium falciparum parasitaemia, gestational age, and gravidity, but do not predict pregnancy outcomes.Factors influencing the induction of high affinity antibodies to Plasmodium falciparum merozoite antigens and how affinity changes over time.Association of Antibodies to VAR2CSA and Merozoite Antigens with Pregnancy Outcomes in Women Living in Yaoundé, Cameroon Global genetic diversity of var2csa in Plasmodium falciparum with implications for malaria in pregnancy and vaccine development

P2860

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P2860

High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria.

http://www.wikidata.org/entity/Q34326742

description

2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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High avidity antibodies to ful ...... absence of placental malaria.

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High avidity antibodies to ful ...... absence of placental malaria.

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High avidity antibodies to ful ...... absence of placental malaria.

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High avidity antibodies to ful ...... absence of placental malaria.

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High avidity antibodies to ful ...... absence of placental malaria.

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High avidity antibodies to ful ...... absence of placental malaria.

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High avidity antibodies to ful ...... absence of placental malaria.

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Diane Wallace Taylor

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Ian S Pagano

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Joseph D Smith

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Josephine Fogako

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Marion Avril

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Rose G F Leke

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Simon Ako

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Yeung Lo Tutterrow

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P2860

An analysis of malaria in pregnancy in Africa

Analysis of IgG with specificity for variant surface antigens expressed by placental Plasmodium falciparum isolates

Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria

Multiplex assay for simultaneous measurement of antibodies to multiple Plasmodium falciparum antigens

MF59 adjuvant enhances diversity and affinity of antibody-mediated immune response to pandemic influenza vaccines.

HIV impairs opsonic phagocytic clearance of pregnancy-associated malaria parasites.

Cross-reactive surface epitopes on chondroitin sulfate A-adherent Plasmodium falciparum-infected erythrocytes are associated with transcription of var2csa.

Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental Plasmodium falciparum-infected erythrocytes.

Ex vivo desequestration of Plasmodium falciparum-infected erythrocytes from human placenta by chondroitin sulfate A.

Gravidity-dependent production of antibodies that inhibit binding of Plasmodium falciparum-infected erythrocytes to placental chondroitin sulfate proteoglycan during pregnancy

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