Immunization with chaperone-peptide complex induces low-avidity cytotoxic T lymphocytes providing transient protection against herpes simplex virus infection
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Phase I Dose-Escalation Study of a Monovalent Heat Shock Protein 70-Herpes Simplex Virus Type 2 (HSV-2) Peptide-Based Vaccine Designed To Prime or Boost CD8 T-Cell Responses in HSV-Naive and HSV-2-Infected SubjectsHsp70 enhances presentation of FMDV antigen to bovine CD4+ T cells in vitro.Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function.Recent progress in herpes simplex virus immunobiology and vaccine researchTh-cytotoxic T-lymphocyte chimeric epitopes extended by Nepsilon-palmitoyl lysines induce herpes simplex virus type 1-specific effector CD8+ Tc1 responses and protect against ocular infection.High efficiency CD91- and LOX-1-mediated re-presentation of gp96-chaperoned peptides by MHC II molecules.Hsp110-mediated enhancement of CD4+ T cell responses to the envelope glycoprotein of members of the family Flaviviridae in vitro does not occur in vivoVaccination with heat shock protein-peptide complexes: from basic science to clinical applications.DNA vaccines expressing antigens with a stress protein-capturing domain display enhanced immunogenicity.Herpes simplex virus-2 glycoprotein interaction with HVEM influences virus-specific recall cellular responses at the mucosa.Recombinant Listeria monocytogenes expressing an immunodominant peptide fails to protect after intravaginal challenge with herpes simplex virus-2Herpes simplex virus type 2 tegument proteins contain subdominant T-cell epitopes detectable in BALB/c mice after DNA immunization and infectionAn intranasal heat shock protein based vaccination strategy confers protection against mucosal challenge with herpes simplex virusAntigenic peptides complexed to phylogenically diverse Hsp70s induce differential immune responses.Heat shock protein 70 enhances mucosal immunity against human norovirus when coexpressed from a vesicular stomatitis virus vector.The immunological era in melanoma treatment: new challenges for heat shock protein-based vaccine in the advanced disease.In vivo rescue of defective memory CD8+ T cells by cognate helper T cells.Exogenous heat shock protein 70 mediates sepsis manifestations and decreases the mortality rate in rats.
P2860
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P2860
Immunization with chaperone-peptide complex induces low-avidity cytotoxic T lymphocytes providing transient protection against herpes simplex virus infection
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Immunization with chaperone-pe ...... herpes simplex virus infection
@ast
Immunization with chaperone-pe ...... herpes simplex virus infection
@en
Immunization with chaperone-pe ...... herpes simplex virus infection
@nl
type
label
Immunization with chaperone-pe ...... herpes simplex virus infection
@ast
Immunization with chaperone-pe ...... herpes simplex virus infection
@en
Immunization with chaperone-pe ...... herpes simplex virus infection
@nl
prefLabel
Immunization with chaperone-pe ...... herpes simplex virus infection
@ast
Immunization with chaperone-pe ...... herpes simplex virus infection
@en
Immunization with chaperone-pe ...... herpes simplex virus infection
@nl
P2093
P2860
P921
P1433
P1476
Immunization with chaperone-pe ...... herpes simplex virus infection
@en
P2093
Barry D Bruce
Barry T Rouse
Malgorzata Gierynska
Shanna Norman
Udayasankar Kumaraguru
P2860
P304
P356
10.1128/JVI.76.1.136-141.2002
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P577
2002-01-01T00:00:00Z