N-arginine dibasic convertase, a metalloendopeptidase as a prototype of a class of processing enzymes.
about
Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase familyGene expression of the dibasic-pair cleaving enzyme NRD convertase (N-arginine dibasic convertase) is differentially regulated in the GH3 pituitary and Mat-Lu prostate cell linesThe metalloendopeptidase nardilysin (NRDc) is potently inhibited by heparin-binding epidermal growth factor-like growth factor (HB-EGF)N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration.Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrationsA role for a protease in morphogenic responses during yeast cell fusion.Fusion of a fission yeastLoss of Nardilysin, a Mitochondrial Co-chaperone for α-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and NeurodegenerationCritical roles of nardilysin in the maintenance of body temperature homoeostasisA chloroplast processing enzyme involved in precursor maturation shares a zinc-binding motif with a recently recognized family of metalloendopeptidases.Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase.Expression of type II chorionic gonadotropin genes supports a role in the male reproductive systemNRD1, which encodes nardilysin protein, promotes esophageal cancer cell invasion through induction of MMP2 and MMP3 expression.The use of chromium(III) to supercharge peptides by protonation at low basicity sites.Identification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signalling via enhanced ectodomain shedding of TNF-α.The Novel Actions of the Metabolite GnRH-(1-5) are Mediated by a G Protein-Coupled Receptor.Reduced neuronal co-localisation of nardilysin and the putative alpha-secretases ADAM10 and ADAM17 in Alzheimer's disease and Down syndrome brains.Nardilysin convertase regulates the function of the maxi-K channel isoform mK44 in human myometriumA mechanism for epithelial-mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3).Nardilysin in human brain diseases: both friend and foe.Nardilysin regulates inflammation, metaplasia, and tumors in murine stomach.Tubulin potentiates the interaction of the metalloendopeptidase nardilysin with the neuronal scaffold protein p42IP4/centaurin-α1 (ADAP1).Ultrastructural localization and distribution of Nardilysin in mammalian male germ cells.Two novel metallopeptidases with a specificity for basic residues: functional properties, structure and cellular distribution.Nardilysin is involved in autoimmune arthritis via the regulation of tumour necrosis factor alpha secretionSquid spermiogenesis: molecular characterization of testis-specific pro-protamines.The Effects of Trivalent Lanthanide Cationization on the Electron Transfer Dissociation of Acidic Fibrinopeptide B and its Analogs.Association of insulin-degrading enzyme with a 70 kDa cytosolic protein in hepatoma cells.N-arginine dibasic convertase (nardilysin) isoforms are soluble dibasic-specific metalloendopeptidases that localize in the cytoplasm and at the cell surface.Interaction of the brain-specific protein p42IP4/centaurin-alpha1 with the peptidase nardilysin is regulated by the cognate ligands of p42IP4, PtdIns(3,4,5)P3 and Ins(1,3,4,5)P4, with stereospecificity.
P2860
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P2860
N-arginine dibasic convertase, a metalloendopeptidase as a prototype of a class of processing enzymes.
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
N-arginine dibasic convertase, ...... a class of processing enzymes.
@ast
N-arginine dibasic convertase, ...... a class of processing enzymes.
@en
N-arginine dibasic convertase, ...... a class of processing enzymes.
@nl
type
label
N-arginine dibasic convertase, ...... a class of processing enzymes.
@ast
N-arginine dibasic convertase, ...... a class of processing enzymes.
@en
N-arginine dibasic convertase, ...... a class of processing enzymes.
@nl
prefLabel
N-arginine dibasic convertase, ...... a class of processing enzymes.
@ast
N-arginine dibasic convertase, ...... a class of processing enzymes.
@en
N-arginine dibasic convertase, ...... a class of processing enzymes.
@nl
P2093
P2860
P356
P1476
N-arginine dibasic convertase, ...... a class of processing enzymes.
@en
P2093
Chesneau V
Leseney AM
Pierotti AR
P2860
P304
P356
10.1073/PNAS.91.13.6078
P407
P577
1994-06-01T00:00:00Z