Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2. - Wikidata - awgldk - TriplyDB

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

http://www.wikidata.org/entity/Q34329323

about

Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA)Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils Group V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2 Purification and characterization of a membrane-associated 48-kilodalton phospholipase A(2) in leaves of broad bean Cytosolic phospholipase A2 in rat decidual cells: evidence for its role in decidualization Endothelium-dependent metabolism by endocannabinoid hydrolases and cyclooxygenases limits vasorelaxation to anandamide and 2-arachidonoylglycerol Membrane tubule-mediated reassembly and maintenance of the Golgi complex is disrupted by phospholipase A2 antagonists Evidence that phospholipase A2 activity is required for Golgi complex and trans Golgi network membrane tubulation Cytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death.Blockade of eosinophil migration and airway hyperresponsiveness by cPLA2-inhibition.Pasteurella haemolytica leukotoxin-induced increase in phospholipase A2 activity in bovine neutrophils.Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease.Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.Oxidative signaling in renal epithelium: Critical role of cytosolic phospholipase A2 and p38(SAPK).Purification and characterization of a cytosolic Ca(2+)-independent phospholipase A(2) from bovine brain.Interleukin 1 alpha causes rapid activation of cytosolic phospholipase A2 by phosphorylation in rat mesangial cells.Interfacial kinetic and binding properties of mammalian group IVB phospholipase A2 (cPLA2beta) and comparison with the other cPLA2 isoforms.An LPA species (18:1 LPA) plays key roles in the self-amplification of spinal LPA production in the peripheral neuropathic pain model.Apamin-sensitive, non-nitric oxide (NO) endothelium-dependent relaxations to bradykinin in the bovine isolated coronary artery: no role for cytochrome P450 and K+.Bromoenol lactone enhances the permeabilization of rat submandibular acinar cells by P2X7 agonists.Cytosolic phospholipase A2 protein as a novel therapeutic target for spinal cord injury Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes.Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2.cPLA(2)α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: a positive feedback loop The ω3-polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A(2) and suppress PGE(2) formation in mesangial cells Trafficking of endogenous smooth muscle cell cholesterol: a role for serum amyloid A and interleukin-1β Polychlorinated biphenyls induce arachidonic acid release in human platelets in a tamoxifen sensitive manner via activation of group IVA cytosolic phospholipase A2-alpha.Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis Synthesis of polyfluoro ketones for selective inhibition of human phospholipase A2 enzymes.Calcium-independent phospholipases in the heart: mediators of cellular signaling, bioenergetics, and ischemia-induced electrophysiologic dysfunction Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH).Protein kinase C-dependent activation of cytosolic phospholipase A2 and mitogen-activated protein kinase by alpha 1-adrenergic receptors in Madin-Darby canine kidney cells.Alterations in membrane transport function and cell viability induced by ATP depletion in primary cultured rabbit renal proximal tubular cells.Phospholipase A2, oxidative stress, and neurodegeneration in binge ethanol-treated organotypic slice cultures of developing rat brain.Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation.Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases.Regulation of the arachidonic acid mobilization in macrophages by combustion-derived particles.Activation of BK channels in GH3 cells by a c-PLA2-dependent G-protein signaling pathway.

P2860

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P2860

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

http://www.wikidata.org/entity/Q34329323

description

1993 nî lūn-bûn

@nan

1993 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1993 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1993年の論文

@ja

1993年論文

@yue

1993年論文

@zh-hant

1993年論文

@zh-hk

1993年論文

@zh-mo

1993年論文

@zh-tw

1993年论文

@wuu

name

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@ast

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@en

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@nl

type

label

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@ast

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@en

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@nl

prefLabel

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@ast

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@en

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@nl

P1433

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Q34329323-6E7B0046-21F0-42F2-9850-656A540EB88B

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P1433

P1476

Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.

@en

P2093

F Ghomashchi

http://www.w3.org/2001/XMLSchema#string

F Laliberté

http://www.w3.org/2001/XMLSchema#string

H K Lin

http://www.w3.org/2001/XMLSchema#string

H Perrier

http://www.w3.org/2001/XMLSchema#string

I P Street

http://www.w3.org/2001/XMLSchema#string

M H Gelb

http://www.w3.org/2001/XMLSchema#string

N M Tremblay

http://www.w3.org/2001/XMLSchema#string

P K Weech

http://www.w3.org/2001/XMLSchema#string

Z Huang

http://www.w3.org/2001/XMLSchema#string

Z Wang

http://www.w3.org/2001/XMLSchema#string

P304

5935-5940

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/BI00074A003

http://www.w3.org/2001/XMLSchema#string

P407

P433

23

http://www.w3.org/2001/XMLSchema#string

P478

32

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P577

1993-06-01T00:00:00Z

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P698

8018213

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