Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state.
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High-Fidelity Reprogrammed Human IPSCs Have a High Efficacy of DNA Repair and Resemble hESCs in Their MYC Transcriptional SignatureSustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markersDifferential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells.Epigenome Maintenance in Response to DNA DamageDNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cellsInhibition of histone deacetylases enhances DNA damage repair in SCNT embryos.The onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either alleleThe developmental potential of iPSCs is greatly influenced by reprogramming factor selectionHigh-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells.Mechanisms and models of somatic cell reprogramming.p53: the barrier to cancer stem cell formation.Advanced feeder-free generation of induced pluripotent stem cells directly from blood cells.Stem cells: the pursuit of genomic stability.Concise review: workshop review: understanding and assessing the risks of stem cell-based therapiesCtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem CellsMechanisms underlying the formation of induced pluripotent stem cells.Concurrent progress of reprogramming and gene correction to overcome therapeutic limitation of mutant ALK2-iPSC.Genetic and epigenetic variations in iPSCs: potential causes and implications for applicationThe cnidarian Hydractinia echinata employs canonical and highly adapted histones to pack its DNAAnalysis of induced pluripotent stem cells from a BRCA1 mutant family.Integrating Gene Correction in the Reprogramming and Transdifferentiation Processes: A One-Step Strategy to Overcome Stem Cell-Based Gene Therapy Limitations.Antioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells.DNA double-strand breaks in human induced pluripotent stem cell reprogramming and long-term in vitro culturingThe intertwined roles of transcription and repair proteins.Concise review: induced pluripotency by defined factors: prey of oxidative stress.Regulation of Reprogramming and Cellular Plasticity through Histone Exchange and Histone Variant Incorporation.Bringing Neural Cell Therapies to the Clinic: Past and Future Strategies.Genetic susceptibility to cutaneous radiation injury.Influence of ATM-Mediated DNA Damage Response on Genomic Variation in Human Induced Pluripotent Stem Cells.Rad51 Regulates Reprogramming Efficiency through DNA Repair Pathway.Genomic instability during reprogramming by nuclear transfer is DNA replication dependent.Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process.Generation of iPSCs from genetically corrected Brca2 hypomorphic cells: implications in cell reprogramming and stem cell therapy.Tying genetic stability to cell identity.Perspectives on gene therapy for Fanconi anemia
P2860
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P2860
Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state.
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2013 թուականի Մարտին հրատարակուած գիտական յօդուած
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2013 թվականի մարտին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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Homologous recombination DNA r ...... amming to a pluripotent state.
@ast
Homologous recombination DNA r ...... amming to a pluripotent state.
@en
Homologous recombination DNA r ...... amming to a pluripotent state.
@nl
type
label
Homologous recombination DNA r ...... amming to a pluripotent state.
@ast
Homologous recombination DNA r ...... amming to a pluripotent state.
@en
Homologous recombination DNA r ...... amming to a pluripotent state.
@nl
prefLabel
Homologous recombination DNA r ...... amming to a pluripotent state.
@ast
Homologous recombination DNA r ...... amming to a pluripotent state.
@en
Homologous recombination DNA r ...... amming to a pluripotent state.
@nl
P2093
P2860
P50
P1433
P1476
Homologous recombination DNA r ...... amming to a pluripotent state.
@en
P2093
Daniela Georgieva
Fabio Vanoli
Maria Jasin
Thomas Ludwig
Zhong-Dong Shi
P2860
P304
P356
10.1016/J.CELREP.2013.02.005
P577
2013-03-07T00:00:00Z