LpxC inhibitors as new antibacterial agents and tools for studying regulation of lipid A biosynthesis in Gram-negative pathogens. - Wikidata - awgldk - TriplyDB

LpxC inhibitors as new antibacterial agents and tools for studying regulation of lipid A biosynthesis in Gram-negative pathogens.

LpxC inhibitors as new antibacterial agents and tools for studying regulation of lipid A biosynthesis in Gram-negative pathogens.

http://www.wikidata.org/entity/Q34334699

about

Regulated Control of the Assembly and Diversity of LPS by Noncoding sRNAs Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii Mutant Alleles of lptD Increase the Permeability of Pseudomonas aeruginosa and Define Determinants of Intrinsic Resistance to Antibiotics.Transport of lipopolysaccharide to the Gram-negative bacterial cell surface.Translational deficiencies in antibacterial discovery and new screening paradigms.Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC.LpxC inhibitors: a patent review (2010-2016).New molecules and adjuvants in the treatment of infections by Acinetobacter baumannii.Antibacterial Drug Discovery Targeting the Lipopolysaccharide Biosynthetic Enzyme LpxC.Using bacterial genomes and essential genes for the development of new antibiotics.Structure, inhibition, and regulation of essential lipid A enzymes.Susceptibility of Clinical Isolates of Burkholderia pseudomallei to a Lipid A Biosynthesis Inhibitor.High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors.Genomics and Susceptibility Profiles of Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa from Spain.In Vitro and In Vivo Efficacy of an LpxC Inhibitor, CHIR-090, Alone or Combined with Colistin against Pseudomonas aeruginosa Biofilm.Expanding the paradigm for the outer membrane: Acinetobacter baumannii in the absence of endotoxin.Genetic mechanisms of Coxiella burnetii lipopolysaccharide phase variation.The Biosynthesis of Lipooligosaccharide from Bacteroides thetaiotaomicron.Lipid A Has Significance for Optimal Growth of Coxiella burnetii in Macrophage-Like THP-1 Cells and to a Lesser Extent in Axenic Media and Non-phagocytic Cells.

P2860

Q26776000-177B3C54-32C7-4035-8DDA-602F4CF12936 Q33911762-59B48595-C498-41B0-A057-7D765517345C Q37120148-B9CB081A-8E61-4A4A-BA22-A019E2482857 Q38367630-520E5494-9B1A-4D58-B71A-78EF3C1A4089 Q38514161-FBE0EA9F-5798-446A-AA42-0F010D59FD3C Q38584143-263FC005-B0A9-4C04-8104-3EFA3DF7299D Q38661567-0D316E75-59EE-40CB-99E0-0BDE550D7BA0 Q38662413-C554E33E-27D9-4B09-B166-1F5ED844F9CB Q38805100-18FBB30F-6898-4CFC-B96C-51BB8E2A348B Q38846788-667F795A-F2D1-4A4C-B878-F6AB7373E2C1 Q39035296-F8D3FE4C-769B-4DAB-B12A-14FD8CFE4C01 Q39035338-3A2FA507-38DC-4613-875F-DFB811E7B8D1 Q39446204-22F2CE97-BACB-41AB-B4FF-CE1E29CF1303 Q39665406-EE054C6B-8742-4578-AEE7-6A9CDB0FA741 Q40056971-19BD6FC6-0DF1-4203-931D-60DF8E1107E5 Q40230660-5405E6F1-B0F5-44EA-8926-F86460D62C50 Q48346122-BA4C8C34-1147-4B34-9959-A2C9515193A3 Q52685085-71E30B93-B3C0-4A0A-859C-0A6561F6DAB1 Q54942044-0EEF6760-8704-4A37-8D73-1BCF8C8CBCCC Q55229655-A54D539C-3E1C-4DDC-8DA6-77FB640C0F34

P2860

LpxC inhibitors as new antibacterial agents and tools for studying regulation of lipid A biosynthesis in Gram-negative pathogens.

http://www.wikidata.org/entity/Q34334699

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@ast

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@en

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@nl

type

label

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@ast

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@en

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@nl

prefLabel

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@ast

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@en

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@nl

P1433

Q34334699-5502A196-39BF-4F74-98E6-2C1ACE66C123

P1476

Q34334699-15A0034A-A54F-49BE-A6A1-1CF54A494EB0

P2093

Q34334699-1AEB38F0-D262-4022-B849-DAF67811A35C

Q34334699-2F443179-E13C-4CA5-96AF-FF6E4E189359

Q34334699-3E35D116-3D09-4CE0-93C8-DBB74F9B6D04

Q34334699-4C24E56B-6253-4FC0-B241-E25E0127737F

Q34334699-5E9B0120-8E54-437E-886F-311CFDEDB1D2

Q34334699-6E1E9467-8588-4360-8C70-183CFE7F8D09

Q34334699-7E976032-4881-4F67-8987-884EF5AB3901

Q34334699-A6563C55-4989-411C-837F-58B9B30912BA

Q34334699-ABDE5425-5FD3-4A66-9DC4-BBC05FCC74A1

Q34334699-C698230A-DB5F-4557-A0A9-5DC7F29B0557

P2860

Q34334699-0585C59B-56CD-418D-9234-AF2EEC29A11E

Q34334699-09B2870A-A3AB-4A6B-A32B-2CDC47E5E1CD

Q34334699-19A55174-2233-4C6B-B475-3A2E90F46A07

Q34334699-2085DE29-28A7-4737-AA8A-05B186A96915

Q34334699-22B9E8AC-2A4F-40FD-BA17-234379A53BEB

Q34334699-273D60E5-5B12-4A5A-B379-12C6CAA00B52

Q34334699-51D15A5B-0E12-40C1-870D-843C4D804843

Q34334699-5333DEA8-CFC6-4E37-9204-3ED08B91BDE9

Q34334699-60834F93-A81B-4E12-87AC-A35C436E05D0

Q34334699-65A13198-0EB1-4718-9BDF-66103168F74A

P304

Q34334699-88F4CFC4-BAD3-4004-B1B4-4E670596D1CD

P31

Q34334699-B0265D55-4334-4289-9E52-FA9A89665CCA

P356

Q34334699-5D38EB7C-5AE9-4F61-88AA-B870859A0374

P433

Q34334699-ACE086CE-18F7-443F-9154-DC7BC9BEF591

P478

Q34334699-FCEE97C6-3343-4A0A-9890-65A59A187995

P577

Q34334699-9F7BFA9C-076E-4AB4-B031-BB7FE445530B

P698

Q34334699-53B2DDA8-B313-4853-A18B-7EADD5627EA6

P921

Q34334699-FBDDFCA4-CDC1-4614-B45F-CC8F8C632994

P932

Q34334699-6EFADF08-83A9-4421-911B-FCE0B63F46B6

P356

P1433

P1476

LpxC inhibitors as new antibac ...... is in Gram-negative pathogens.

@en

P2093

Alita A Miller

http://www.w3.org/2001/XMLSchema#string

Andrew P Tomaras

http://www.w3.org/2001/XMLSchema#string

Arlene Carifa

http://www.w3.org/2001/XMLSchema#string

Charlene Desbonnet

http://www.w3.org/2001/XMLSchema#string

Craig J McPherson

http://www.w3.org/2001/XMLSchema#string

David George

http://www.w3.org/2001/XMLSchema#string

John P O'Donnell

http://www.w3.org/2001/XMLSchema#string

Justin I Montgomery

http://www.w3.org/2001/XMLSchema#string

Lisa Mullins

http://www.w3.org/2001/XMLSchema#string

Matthew F Brown

http://www.w3.org/2001/XMLSchema#string

P2860

Mfold web server for nucleic acid folding and hybridization prediction

Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans

Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes

An improved method for rapid generation of unmarked Pseudomonas aeruginosa deletion mutants

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding

Potent inhibitors of LpxC for the treatment of Gram-negative infections

Pyridone methylsulfone hydroxamate LpxC inhibitors for the treatment of serious gram-negative infections

MexR repressor of the mexAB-oprM multidrug efflux operon of Pseudomonas aeruginosa: identification of MexR binding sites in the mexA-mexR intergenic region

A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants

P304

e01551-14

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/MBIO.01551-14

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

P577

2014-09-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

25271285

http://www.w3.org/2001/XMLSchema#string

P921

Gram-negative bacteria

P932

4196226

http://www.w3.org/2001/XMLSchema#string