Systematic kinome shRNA screening identifies CDK11 (PITSLRE) kinase expression is critical for osteosarcoma cell growth and proliferation.
about
The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancerTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsTime-lapse imaging of neuroblastoma cells to determine cell fate upon gene knockdownSynergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcomaTFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signalingCyclin-dependent kinase 11 (CDK11) is crucial in the growth of liposarcoma cellsDevelopment and potential applications of CRISPR-Cas9 genome editing technology in sarcoma.Small interfering RNA-based molecular therapy of cancersClinical and biological significance of PIM1 kinase in osteosarcoma.Targeting CDK11 in osteosarcoma cells using the CRISPR-Cas9 system.MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer.Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapyCluster of Differentiation 44 Targeted Hyaluronic Acid Based Nanoparticles for MDR1 siRNA Delivery to Overcome Drug Resistance in Ovarian Cancer.Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib.Cyclin-dependent kinase 11(p110) (CDK11(p110)) is crucial for human breast cancer cell proliferation and growthNsc23925 prevents the development of paclitaxel resistance by inhibiting the introduction of P-glycoprotein and enhancing apoptosis.CDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing.GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migrationCyclin-Dependent Kinase 11 (CDK11) Is Required for Ovarian Cancer Cell Growth In Vitro and In Vivo, and Its Inhibition Causes Apoptosis and Sensitizes Cells to PaclitaxelAndrogen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11.The roles and therapeutic potential of cyclin-dependent kinases (CDKs) in sarcoma.Inhibitors of cyclin-dependent kinases as cancer therapeutics.Kinases Involved in Both Autophagy and Mitosis.DNA methylation of the CDC2L1 gene promoter region decreases the expression of the CDK11p58 protein and reduces apoptosis in keloid fibroblasts.
P2860
Q26751387-7FB3CAAE-86B6-42B0-A1E8-0E543DC41780Q26827580-BF003D77-7B74-4777-B9B2-F9F58AC5F280Q27332436-2CD48692-92FC-4F16-9F6A-31DD91E35193Q28541805-84E6AF1F-BF0C-400E-86D7-681361705647Q33613510-F7474DAC-A857-41DA-A54B-95F533638432Q34027454-61B97571-AA7E-4CC0-BC5B-E3A25EA9AD3EQ34045952-FDACB9CD-9C02-4486-BD42-ACC948C725CAQ34552948-25465107-C4D7-47AD-B09B-93E5D57A35DCQ34674917-46D07683-7877-485A-92BA-9692BF8B7753Q35007531-D14F6EA8-458B-4B4C-98FF-09AF568EC22BQ35089472-12009A8C-F113-48B6-80DE-DE48930F27A4Q35132090-307582CC-2760-49A1-A404-FD3A0CFB2B26Q35587385-091E89EB-606F-487C-B5FE-CCED2A571A1BQ35602598-7D540D9D-1156-4C44-ABCF-B51B065D500AQ35626610-0664A0D3-2A62-44C1-979F-34F5667BFDB7Q35930414-B59078FD-6E8B-4A86-AAF8-97E1D5E4C87CQ36289312-A2BCF0A5-F6E0-4F91-BA05-194BFBE9AFE5Q37046475-0D1F21D5-62B6-4CCF-823D-FD8F908CAB27Q37075249-1A0A31FF-9B2D-4E7F-BC72-67F53B418E7AQ37682137-03B308EA-67CE-41EA-B9D1-3B6F10B4541EQ38669852-C116F0FB-4023-4A94-A3DF-1E5D28F80353Q39125016-171F661B-8341-47C7-985F-E6D202C2F627Q41661088-473168B0-CCC4-45F8-919F-366BF2224430Q47331145-04813EE2-8150-4EEA-8DCB-C2F0AF3DD529
P2860
Systematic kinome shRNA screening identifies CDK11 (PITSLRE) kinase expression is critical for osteosarcoma cell growth and proliferation.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Systematic kinome shRNA screen ...... cell growth and proliferation.
@ast
Systematic kinome shRNA screen ...... cell growth and proliferation.
@en
Systematic kinome shRNA screening identifies CDK11
@nl
type
label
Systematic kinome shRNA screen ...... cell growth and proliferation.
@ast
Systematic kinome shRNA screen ...... cell growth and proliferation.
@en
Systematic kinome shRNA screening identifies CDK11
@nl
prefLabel
Systematic kinome shRNA screen ...... cell growth and proliferation.
@ast
Systematic kinome shRNA screen ...... cell growth and proliferation.
@en
Systematic kinome shRNA screening identifies CDK11
@nl
P2093
P1476
Systematic kinome shRNA screen ...... cell growth and proliferation.
@en
P2093
David Harmon
Francis J Hornicek
Henry Mankin
Jianming Zhang
Nathanael S Gray
Petur Nielsen
Xianzhe Liu
Zhenfeng Duan
P304
P356
10.1158/1078-0432.CCR-12-1157
P407
P50
P577
2012-07-12T00:00:00Z