Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors. - Wikidata - awgldk - TriplyDB

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors.

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors.

http://www.wikidata.org/entity/Q34339449

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Transcriptional regulation of hepatic lipogenesis Redox regulation of FoxO transcription factors Circadian rhythms and metabolism: from the brain to the gut and back again Decreased expression of hepatic glucokinase in type 2 diabetes.A mutant allele encoding DNA binding-deficient FoxO1 differentially regulates hepatic glucose and lipid metabolism Pathogenesis of selective insulin resistance in isolated hepatocytes.Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice.The new biology of diabetes.Transcriptional and Chromatin Regulation during Fasting - The Genomic Era mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2.FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization.FoxO1 Deacetylation Decreases Fatty Acid Oxidation in β-Cells and Sustains Insulin Secretion in Diabetes.Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.The FOXO1 Gene-Obesity Interaction Increases the Risk of Type 2 Diabetes Mellitus in a Chinese Han Population Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins.FOXO transcription factors protect against the diet-induced fatty liver disease.Gastric bypass surgery with exercise alters plasma microRNAs that predict improvements in cardiometabolic risk.Identification of an early transcriptomic signature of insulin resistance and related diseases in lymphomonocytes of healthy subjects.Hypothalamic Insulin Resistance in Obesity: Effects on Glucose Homeostasis.Foxo3 activity promoted by non-coding effects of circular RNA and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis.Nonalcoholic fatty liver disease: cause or consequence of type 2 diabetes?When β-cells fail: lessons from dedifferentiation.NAFLD and diabetes mellitus.Unraveling the Regulation of Hepatic Metabolism by Insulin.Characterization of the direct targets of FOXO transcription factors throughout evolution.A mathematical model of the impact of insulin secretion dynamics on selective hepatic insulin resistance.Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes.FoxO1 is required for most of the metabolic and hormonal perturbations produced by hepatic insulin receptor deletion in male mice.Nutritional regulation of renal lipogenic factor expression in mice: comparison to regulation in the liver and skeletal muscle.Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling.Biochemical and cellular properties of insulin receptor signalling.Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis.SCP4: A Small Nuclear Phosphatase Having a Big Effect on FoxOs in Gluconeogenesis.FoxO transcription factors are required for hepatic HDL-cholesterol clearance.Crystal structures reveal a new and novel FoxO1 binding site within the human glucose-6-phosphatase catalytic subunit 1 gene promoter.The hepatic FOXQ1 transcription factor regulates glucose metabolism in mice.Ethnic Similarities and Differences in the Relationship between Beta Cell Mass and Diabetes.The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer.Insulin Action Research and the Future of Diabetes Treatment: The 2017 Banting Medal for Scientific Achievement Lecture

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Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors.

http://www.wikidata.org/entity/Q34339449

description

2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Integrated control of hepatic ...... es FoxO transcription factors.

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Integrated control of hepatic ...... es FoxO transcription factors.

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Nature Communications

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Integrated control of hepatic ...... res FoxO transcription factors

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Bhavapriya Vaitheesvaran

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Colette M Knight

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Domenico Accili

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Helene L Kammoun

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Irwin J Kurland

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Isabel Arrieta-Cruz

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Kirsten Hartil

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Mark A Febbraio

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Roger Gutierrez-Juarez

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SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects

Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

Mechanisms for insulin resistance: common threads and missing links

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action.

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation

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5190

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10.1038/NCOMMS6190

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5

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Rebecca A Haeusler

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2014-10-13T00:00:00Z

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266909989

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1031598668

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25307742

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4197140

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