HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage - Wikidata - awgldk - TriplyDB

HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage

HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage

http://www.wikidata.org/entity/Q34341388

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Papillomavirus E6 Oncoproteins Take Common Structural Approaches to Solve Different Biological Problems Cutaneous Squamous Cell Carcinomas in Organ Transplant Recipients HPV Carcinomas in Immunocompromised Patients Modulation of DNA damage and repair pathways by human tumour viruses Functional Roles of E6 and E7 Oncoproteins in HPV-Induced Malignancies at Diverse Anatomical Sites The Role of the DNA Damage Response throughout the Papillomavirus Life Cycle Papillomavirus E6 oncoproteins.ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.The transmembrane channel-like protein family and human papillomaviruses: Insights into epidermodysplasia verruciformis and progression to squamous cell carcinoma.DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing.Identification of C/EBPα as a novel target of the HPV8 E6 protein regulating miR-203 in human keratinocytes.Genus beta human papillomavirus E6 proteins vary in their effects on the transactivation of p53 target genes.The ATR signaling pathway is disabled during infection with the parvovirus minute virus of mice.β-HPV 5 and 8 E6 disrupt homology dependent double strand break repair by attenuating BRCA1 and BRCA2 expression and foci formation.HPV vaccination for prevention of skin cancer.Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis.Human papillomaviruses: shared and distinct pathways for pathogenesis STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication.Male human papillomavirus infection post-kidney transplant: an overlooked disease Characterization of three novel human papillomavirus types isolated from oral rinse samples of healthy individuals.Cutaneous HPV8 and MmuPV1 E6 Proteins Target the NOTCH and TGF-β Tumor Suppressors to Inhibit Differentiation and Sustain Keratinocyte Proliferation.DNA damage response is hijacked by human papillomaviruses to complete their life cycle Manipulation of cellular DNA damage repair machinery facilitates propagation of human papillomaviruses.Human Beta-papillomavirus infection and keratinocyte carcinomas.Beta genus papillomaviruses and skin cancer.High Risk Alpha Papillomavirus Oncogenes Impair the Homologous Recombination Pathway.Prognostic variables in high-risk cutaneous squamous cell carcinoma: a review.Molecular Mechanisms of Human Papillomavirus Induced Skin Carcinogenesis Human Papillomavirus and the DNA Damage Response: Exploiting Host Repair Pathways for Viral Replication.Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters.HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition.Beta human papillomavirus E6 expression inhibits stabilization of p53 and increases tolerance of genomic instability.Genomic instability: Ada3 and HPV E6-acetyltransferase connections?Improved detection reveals active β-papillomavirus infection in skin lesions from kidney transplant recipients.Human beta papillomavirus DNA study in primary cutaneous squamous cell carcinomas and their corresponding metastases.Human papillomavirus-associated cutaneous disease burden in human immunodeficiency virus (HIV)-positive patients: the role of human papillomavirus vaccination and a review of the literature.Loss of Genome Fidelity: Beta HPVs and the DNA Damage Response.Induction of Tyrosine Phosphorylation of UV-Activated EGFR by the Beta-Human Papillomavirus Type 8 E6 Leads to Papillomatosis.The interplay of UV and cutaneous papillomavirus infection in skin cancer development.β-HPV Infection Correlates with Early Stages of Carcinogenesis in Skin Tumors and Patient-Derived Xenografts from a Kidney Transplant Recipient Cohort.

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HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage

http://www.wikidata.org/entity/Q34341388

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2012 թվականի հուլիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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name

HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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type

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HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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JOURNAL.PPAT.1002807

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HPV 5 and 8 E6 abrogate ATR ac ...... ence of UVB induced DNA damage

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Denise A Galloway

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Heather L Howie

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Kristin Robinson

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Nicholas A Wallace

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P2860

A role for ATR in the DNA damage-induced phosphorylation of p53

Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Mdm2 promotes the rapid degradation of p53

Degradation of tyrosine phosphatase PTPN3 (PTPH1) by association with oncogenic human papillomavirus E6 proteins.

Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins

Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells

Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins

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e1002807

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10.1371/JOURNAL.PPAT.1002807

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7

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229161745

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22807682

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