Overexpression of interleukin-2 by a recombinant herpes simplex virus type 1 attenuates pathogenicity and enhances antiviral immunity

Overexpression of interleukin-2 by a recombinant herpes simplex virus type 1 attenuates pathogenicity and enhances antiviral immunity

Item
http://www.wikidata.org/entity/Q34344404
IL-2 suppression of IL-12p70 by a recombinant HSV-1 expressing IL-2 induces T-cell auto-reactivity and CNS demyelinationA comparative study of experimental mouse models of central nervous system demyelination.Suppression of IL-12p70 formation by IL-2 or following macrophage depletion causes T-cell autoreactivity leading to CNS demyelination in HSV-1-infected mice.Ocular infection of mice with an avirulent recombinant HSV-1 expressing IL-4 and an attenuated HSV-1 strain generates virulent recombinants in vivo.Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2Mutations within the pathogenic region of herpes simplex virus 1 gK signal sequences alter cell surface expression and neurovirulenceExpression of chicken interleukin-2 by a highly virulent strain of Newcastle disease virus leads to decreased systemic viral load but does not significantly affect mortality in chickens.Role of interleukin-2 and herpes simplex virus 1 in central nervous system demyelination in miceInterrelationship of Primary Virus Replication, Level of Latency, and Time to Reactivation in the Trigeminal Ganglia of Latently Infected Mice.Inclusion of CD80 in HSV targets the recombinant virus to PD-L1 on DCs and allows productive infection and robust immune responses.RNA expression and disease tolerance are associated with a "keystone mutation" in the ochre sea star Pisaster ochraceusThe expression of IL-2 and IL-4 in CD4(+) T cells from mouse lymph nodes and spleen during HSV-1-induced facial palsy.An M2 Rather than a TH2 Response Contributes to Better Protection against Latency Reactivation following Ocular Infection of Naive Mice with a Recombinant Herpes Simplex Virus 1 Expressing Murine Interleukin-4.
P2860

Overexpression of interleukin-2 by a recombinant herpes simplex virus type 1 attenuates pathogenicity and enhances antiviral immunity

Item
http://www.wikidata.org/entity/Q34344404
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Overexpression of interleukin- ...... nd enhances antiviral immunity
@ast
Overexpression of interleukin- ...... nd enhances antiviral immunity
@en
Overexpression of interleukin- ...... nd enhances antiviral immunity
@nl
type
label
Overexpression of interleukin- ...... nd enhances antiviral immunity
@ast
Overexpression of interleukin- ...... nd enhances antiviral immunity
@en
Overexpression of interleukin- ...... nd enhances antiviral immunity
@nl
prefLabel
Overexpression of interleukin- ...... nd enhances antiviral immunity
@ast
Overexpression of interleukin- ...... nd enhances antiviral immunity
@en
Overexpression of interleukin- ...... nd enhances antiviral immunity
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Overexpression of interleukin- ...... nd enhances antiviral immunity
@en
P2093
P2860
P304
P31
P356
10.1128/JVI.76.18.9069-9078.2002
P407
P433
P478
P50
P577
P5875
P698
P921
P932