Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer.
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Bypassing Mechanisms of Mitochondria-Mediated Cancer Stem Cells Resistance to Chemo- and RadiotherapyPotential anti-cancer effect of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a novel histone deacetylase inhibitor, for the treatment of thyroid cancer.Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMTInhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cellsITF2357 transactivates Id3 and regulate TGFβ/BMP7 signaling pathways to attenuate corneal fibrosis.Stathmin1 increases radioresistance by enhancing autophagy in non-small-cell lung cancer cells.Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells.Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells.Emerging approaches for histone deacetylase inhibitor drug discovery.Apoptotic and autophagic pathways with relevant small-molecule compounds, in cancer stem cells.Targeting Chromatin-Mediated Transcriptional Control of Gene Expression in Non-Small Cell Lung Cancer Therapy: Preclinical Rationale and Clinical Results.Clinical relevance of autophagic therapy in cancer: Investigating the current trends, challenges, and future prospects.Epigenetic therapy approaches in non-small cell lung cancer: Update and perspectives.Schedule-dependent increased efficiency of pemetrexed-ionizing radiation combination therapy elicits a differential DNA damage response in lung cancer cells.Vorinostat and metformin sensitize EGFR-TKI resistant NSCLC cells via BIM-dependent apoptosis induction.Gene and MicroRNA Perturbations of Cellular Response to Pemetrexed Implicate Biological Networks and Enable Imputation of Response in Lung Adenocarcinoma.Histone deacetylase inhibitor trichostatin A and autophagy inhibitor chloroquine synergistically exert anti-tumor activity in H-ras transformed breast epithelial cells.Changes in 30K protein synthesis during delayed degeneration of the silk gland by a caspase-dependent pathway in a Bombyx (silkworm) mutant.Histone deacetylase inhibitor ITF2357 leads to apoptosis and enhances doxorubicin cytotoxicity in preclinical models of human sarcoma.
P2860
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P2860
Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer.
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@ast
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@en
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@nl
type
label
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@ast
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@en
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@nl
prefLabel
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@ast
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@en
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@nl
P2093
P2860
P50
P356
P1433
P1476
Histone deacetylase inhibition ...... in non-small cell lung cancer.
@en
P2093
Michele Milella
Ruggero De Maria
Simone Busso
Teresa De Luca
P2860
P2888
P356
10.1186/1476-4598-13-230
P50
P577
2014-10-09T00:00:00Z
P5875
P6179
1048212742