An investigation of the interaction between halofantrine, CYP2D6 and CYP3A4: studies with human liver microsomes and heterologous enzyme expression systems
about
Potentiation of halofantrine-induced QTc prolongation by mefloquine: correlation with blood concentrations of halofantrinePotent inhibition of CYP2D6 by haloperidol metabolites: stereoselective inhibition by reduced haloperidolStereoselective halofantrine disposition and effect: concentration-related QTc prolongationSummary of information on human CYP enzymes: human P450 metabolism data.A microarray-based system for the simultaneous analysis of single nucleotide polymorphisms in human genes involved in the metabolism of anti-malarial drugs.Coprescription of tamoxifen and medications that inhibit CYP2D6.Pharmacokinetics of artemisinin-type compounds.New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme.Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications.Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania.Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.Effect of fluconazole on the pharmacokinetics of halofantrine in healthy volunteers.Predicting drug clearance from recombinantly expressed CYPs: intersystem extrapolation factors.Halofantrine and chloroquine inhibit CYP2D6 activity in healthy Zambians.Effects of tetracycline on the pharmacokinetics of halofantrine in healthy volunteers.Does stereoselective lymphatic absorption contribute to the enantioselective pharmacokinetics of halofantrine In Vivo?Metabolism of artelinic acid to dihydroqinqhaosu by human liver cytochrome P4503A.Toward reduction in animal sacrifice for drugs: molecular modeling of Macaca fascicularis P450 2C20 for virtual screening of Homo sapiens P450 2C8 substrates.
P2860
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P2860
An investigation of the interaction between halofantrine, CYP2D6 and CYP3A4: studies with human liver microsomes and heterologous enzyme expression systems
description
1995 nî lūn-bûn
@nan
1995 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
An investigation of the intera ...... gous enzyme expression systems
@ast
An investigation of the intera ...... gous enzyme expression systems
@en
An investigation of the intera ...... gous enzyme expression systems
@nl
type
label
An investigation of the intera ...... gous enzyme expression systems
@ast
An investigation of the intera ...... gous enzyme expression systems
@en
An investigation of the intera ...... gous enzyme expression systems
@nl
prefLabel
An investigation of the intera ...... gous enzyme expression systems
@ast
An investigation of the intera ...... gous enzyme expression systems
@en
An investigation of the intera ...... gous enzyme expression systems
@nl
P2093
P2860
P1476
An investigation of the intera ...... gous enzyme expression systems
@en
P2093
N R Kitteringham
R C Halliday
P2860
P304
P356
10.1111/J.1365-2125.1995.TB04559.X
P407
P577
1995-10-01T00:00:00Z