Genome-wide inference of natural selection on human transcription factor binding sites. - Wikidata - awgldk - TriplyDB

Genome-wide inference of natural selection on human transcription factor binding sites.

Genome-wide inference of natural selection on human transcription factor binding sites.

http://www.wikidata.org/entity/Q34349585

about

Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune response Comparative primate genomics: emerging patterns of genome content and dynamics Mechanisms of mutational robustness in transcriptional regulation The genetic and mechanistic basis for variation in gene regulation Ancient gene flow from early modern humans into Eastern Neanderthals An expanded sequence context model broadly explains variability in polymorphism levels across the human genome A general framework for estimating the relative pathogenicity of human genetic variants Natural Selection and Functional Potentials of Human Noncoding Elements Revealed by Analysis of Next Generation Sequencing Data dbPSHP: a database of recent positive selection across human populations.Robust forward simulations of recurrent hitchhiking Genome-wide inference of ancestral recombination graphs.Genome-wide signals of positive selection in strongylocentrotid sea urchins.Evidence for widespread positive and negative selection in coding and conserved noncoding regions of Capsella grandiflora.A method for calculating probabilities of fitness consequences for point mutations across the human genome A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes.Viral enhancer mimicry of host innate-immune promoters.Approximation to the distribution of fitness effects across functional categories in human segregating polymorphisms.Signatures of positive selection in the cis-regulatory sequences of the human oxytocin receptor (OXTR) and arginine vasopressin receptor 1a (AVPR1A) genes.Populational landscape of INDELs affecting transcription factor-binding sites in humans.Natural selection in a population of Drosophila melanogaster explained by changes in gene expression caused by sequence variation in core promoter regions.Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding?Gains and Losses of Transcription Factor Binding Sites in Saccharomyces cerevisiae and Saccharomyces paradoxus Negative selection maintains transcription factor binding motifs in human cancer.Fast, scalable prediction of deleterious noncoding variants from functional and population genomic data.Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants.Estimating the mutation load in human genomes The Role of Deleterious Substitutions in Crop Genomes.A novel test for selection on cis-regulatory elements reveals positive and negative selection acting on mammalian transcriptional enhancers.Cis-regulatory variation: significance in biomedicine and evolution.Cis-regulatory elements and human evolution Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder.Evolution of Brain Active Gene Promoters in Human Lineage Towards the Increased Plasticity of Gene Regulation.Estimating the prevalence of functional exonic splice regulatory information.Identification of Lineage-Specific Cis-Regulatory Modules Associated with Variation in Transcription Factor Binding and Chromatin Activity Using Ornstein-Uhlenbeck Models Translating natural genetic variation to gene expression in a computational model of the Drosophila gap gene regulatory network.Adaptive evolution of testis-specific, recently evolved, clustered miRNAs in Drosophila.The impact of rare variation on gene expression across tissues.Promoter shape varies across populations and affects promoter evolution and expression noise.Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment.Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds.

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Genome-wide inference of natural selection on human transcription factor binding sites.

http://www.wikidata.org/entity/Q34349585

description

2013 nî lūn-bûn

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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2013 թվականի հունիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Genome-wide inference of natural selection on human transcription factor binding sites.

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Genome-wide inference of natural selection on human transcription factor binding sites.

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Genome-wide inference of natural selection on human transcription factor binding sites.

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type

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Genome-wide inference of natural selection on human transcription factor binding sites.

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Genome-wide inference of natural selection on human transcription factor binding sites.

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Genome-wide inference of natural selection on human transcription factor binding sites.

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Genome-wide inference of natural selection on human transcription factor binding sites.

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Genome-wide inference of natural selection on human transcription factor binding sites.

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Genome-wide inference of natural selection on human transcription factor binding sites.

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Nature Genetics

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Genome-wide inference of natural selection on human transcription factor binding sites.

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Alon Keinan

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Brad Gulko

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Ilan Gronau

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Leonardo Arbiza

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Melissa J Hubisz

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Patterns of positive selection in six Mammalian genomes

Evolution at two levels: on genes and form

The distribution of fitness effects of new deleterious amino acid mutations in humans

Evolutionary and Biomedical Insights from the Rhesus Macaque Genome

A Draft Sequence of the Neandertal Genome

Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding

An integrated encyclopedia of DNA elements in the human genome

Comparative and demographic analysis of orang-utan genomes

Slightly Deleterious Mutant Substitutions in Evolution

Initial sequence of the chimpanzee genome and comparison with the human genome

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10.1038/NG.2658

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7

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Bülent Arman Aksoy

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2013-06-09T00:00:00Z

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237095061

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