Probing the effect of promoters on noise in gene expression using thousands of designed sequences.
about
Homotypic clusters of transcription factor binding sites: A model system for understanding the physical mechanics of gene expressionSort-seq under the hood: implications of design choices on large-scale characterization of sequence-function relationsBarcode Sequencing Screen Identifies SUB1 as a Regulator of Yeast Pheromone Inducible GenesNatural yeast promoter variants reveal epistasis in the generation of transcriptional-mediated noise and its potential benefit in stressful conditions.Effect of transcription factor resource sharing on gene expression noiseSequence-based model of gap gene regulatory network.Understanding how cis-regulatory function is encoded in DNA sequence using massively parallel reporter assays and designed sequences.Expression noise facilitates the evolution of gene regulation.The Low Noise Limit in Gene ExpressionFunction does not follow form in gene regulatory circuitsStructure of silent transcription intervals and noise characteristics of mammalian genesThe Role of Genome Accessibility in Transcription Factor Binding in Bacteria.MPRAnator: a web-based tool for the design of massively parallel reporter assay experimentsVariation is function: Are single cell differences functionally important?: Testing the hypothesis that single cell variation is required for aggregate functionAffinity and competition for TBP are molecular determinants of gene expression noise.Contrasting Frequencies and Effects of cis- and trans-Regulatory Mutations Affecting Gene Expression.How motif environment influences transcription factor search dynamics: Finding a needle in a haystackSequences flanking the core-binding site modulate glucocorticoid receptor structure and activity.A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity.Large-scale mapping of gene regulatory logic reveals context-dependent repression by transcriptional activators.Independent regulation of gene expression level and noise by histone modificationsUniversal protein distributions in a model of cell growth and division.Taking chances and making mistakes: non-genetic phenotypic heterogeneity and its consequences for surviving in dynamic environmentsTranslating natural genetic variation to gene expression in a computational model of the Drosophila gap gene regulatory network.Facilitated diffusion buffers noise in gene expression.Study of in vitro transcriptional binding effects and noise using constitutive promoters combined with UP element sequences in Escherichia coli.Multiple binding sites for transcriptional repressors can produce regular bursting and enhance noise suppression.The Evolution of Gene-Specific Transcriptional Noise Is Driven by Selection at the Pathway Level.In silico design of context-responsive mammalian promoters with user-defined functionality.Unraveling the determinants of microRNA mediated regulation using a massively parallel reporter assay.The coupled effect of nucleosome organization on gene transcription level and transcriptional plasticity.TFIID or not TFIID, a continuing transcriptional SAGA.Single-cell protein dynamics reproduce universal fluctuations in cell populations.A Promoter Variant Confers Constitutive Noisy Bimodal Expression That Increases Oxidative Stress Resistance in YeastGenome-wide analysis of fitness data and its application to improve metabolic modelsFitness effects of altering gene expression noise in
P2860
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P2860
Probing the effect of promoters on noise in gene expression using thousands of designed sequences.
description
2014 nî lūn-bûn
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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Probing the effect of promoter ...... ousands of designed sequences.
@ast
Probing the effect of promoter ...... ousands of designed sequences.
@en
Probing the effect of promoter ...... ousands of designed sequences.
@nl
type
label
Probing the effect of promoter ...... ousands of designed sequences.
@ast
Probing the effect of promoter ...... ousands of designed sequences.
@en
Probing the effect of promoter ...... ousands of designed sequences.
@nl
prefLabel
Probing the effect of promoter ...... ousands of designed sequences.
@ast
Probing the effect of promoter ...... ousands of designed sequences.
@en
Probing the effect of promoter ...... ousands of designed sequences.
@nl
P2093
P2860
P356
P1433
P1476
Probing the effect of promoter ...... ousands of designed sequences.
@en
P2093
David van Dijk
Eilon Sharon
Ohad Manor
Yael Kalma
Zohar Yakhini
P2860
P304
P356
10.1101/GR.168773.113
P577
2014-07-16T00:00:00Z