Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance - Wikidata - awgldk - TriplyDB

Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance

Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance

http://www.wikidata.org/entity/Q34351109

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Drug-resistant genotypes and multi-clonality in Plasmodium falciparum analysed by direct genome sequencing from peripheral blood of malaria patients The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine HIV-positive nigerian adults harbor significantly higher serum lumefantrine levels than HIV-negative individuals seven days after treatment for Plasmodium falciparum infection.Four human Plasmodium species quantification using droplet digital PCR Comparison of methods for detecting asymptomatic malaria infections in the China-Myanmar border area Limitations of Rapid Diagnostic Testing in Patients with Suspected Malaria: A Diagnostic Accuracy Evaluation from Swaziland, a Low-Endemicity Country Aiming for Malaria Elimination.Molecular Markers for Sensitive Detection of Plasmodium falciparum Asexual Stage Parasites and their Application in a Malaria Clinical Trial.The usefulness of rapid diagnostic tests in the new context of low malaria transmission in Zanzibar High-throughput ultrasensitive molecular techniques for quantifying low-density malaria parasitemias.Examining Plasmodium falciparum and P. vivax clearance subsequent to antimalarial drug treatment in the Myanmar-China border area based on quantitative real-time polymerase chain reaction No evidence of delayed parasite clearance after oral artesunate treatment of uncomplicated falciparum malaria in Mali.Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia.A deep sequencing tool for partitioning clearance rates following antimalarial treatment in polyclonal infections.Rational deployment of antimalarial drugs in Africa: should first-line combination drugs be reserved for paediatric malaria cases?Prevalence of PCR detectable malaria infection among febrile patients with a negative Plasmodium falciparum specific rapid diagnostic test in Zanzibar.Malaria surveillance in the Democratic Republic of the Congo: comparison of microscopy, PCR, and rapid diagnostic test.Genetic evaluation of the performance of malaria parasite clearance rate metrics.Ahead of the curve: next generation estimators of drug resistance in malaria infections.Clinical evaluation of a loop-mediated amplification kit for diagnosis of imported malaria Selective sweep suggests transcriptional regulation may underlie Plasmodium vivax resilience to malaria control measures in Cambodia.Malaria diagnostics: now and the future.Partner-Drug Resistance and Population Substructuring of Artemisinin-Resistant Plasmodium falciparum in Cambodia.Investigating the prevalence of transfusion transmission of Plasmodium within a hyperendemic blood donation system.Residual Plasmodium falciparum parasitemia in Kenyan children after artemisinin-combination therapy is associated with increased transmission to mosquitoes and parasite recurrence Randomised controlled trial of two sequential artemisinin-based combination therapy regimens to treat uncomplicated falciparum malaria in African children: a protocol to investigate safety, efficacy and adherence.Plasmodium falciparum parasites with histidine-rich protein 2 (pfhrp2) and pfhrp3 gene deletions in two endemic regions of Kenya.Guideline: the laboratory diagnosis of malaria. General Haematology Task Force of the British Committee for Standards in Haematology.Monitoring artemisinin resistance in Plasmodium falciparum: comparison of parasite clearance time by microscopy and real-time PCR and evaluation of mutations in Pfatpase6 gene in Odisha state of India.Effect of individual and community-level bed net usage on malaria prevalence among under-fives in the Democratic Republic of Congo.Plasmodium falciparum genetic variation of var2csa in the Democratic Republic of the Congo.Genomic Analyses Reveal the Common Occurrence and Complexity of Plasmodium vivax Relapses in Cambodia.Plasmodium-associated changes in human odor attract mosquitoes.Effectiveness and safety of 3 and 5 day courses of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar.

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Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance

http://www.wikidata.org/entity/Q34351109

description

2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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Malaria Journal

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Alice C Eziefula

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Julie Watson

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Rachel L Hallett

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Spencer D Polley

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Stephen G Wright

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P2860

Qinghaosu (Artemisinin): The Price of Success

Artemisinin Resistance in Plasmodium falciparum Malaria

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

Assessment of the pharmacodynamic properties of antimalarial drugs in vivo

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Chloroquine/sulphadoxine-pyrimethamine for gambian children with malaria: transmission to mosquitoes of multidrug-resistant Plasmodium falciparum

Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum.

High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia.

Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally.

In vivo parasitological measures of artemisinin susceptibility

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9

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Colin J Sutherland

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Khalid B Beshir

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