Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain. - Wikidata - awgldk - TriplyDB

Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain.

Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain.

http://www.wikidata.org/entity/Q34351740

about

Trafficking regulates the subcellular distribution of voltage-gated sodium channels in primary sensory neurons Cellular hyper-excitability caused by mutations that alter the activation process of voltage-gated sodium channels Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA Voltage-gated sodium channel expression in mouse DRG after SNI leads to re-evaluation of projections of injured fibers.An approach to identify microRNAs involved in neuropathic pain following a peripheral nerve injury.Nedd4-2 (NEDD4L) controls intracellular Na(+)-mediated activity of voltage-gated sodium channels in primary cortical neurons.Regulation of membrane excitability: a convergence on voltage-gated sodium conductance.Post-translational modifications of voltage-gated sodium channels in chronic pain syndromes Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells.Nedd4-2 haploinsufficiency causes hyperactivity and increased sensitivity to inflammatory stimuli Hierarchical CRMP2 posttranslational modifications control NaV1.7 function.TrkA in vivo function is negatively regulated by ubiquitination.HECT-type E3 ubiquitin ligases in nerve cell development and synapse physiology.Ubiquitination and the Regulation of Membrane Proteins.A Review on Ubiquitination of Neurotrophin Receptors: Facts and Perspectives.PKC-NF-κB are involved in CCL2-induced Nav1.8 expression and channel function in dorsal root ganglion neurons Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).Gene Expression Profiling of Cutaneous Injured and Non-Injured Nociceptors in SNI Animal Model of Neuropathic Pain.Investigation of the possible association of NEDD4-2 (NEDD4L) gene with idiopathic photosensitive epilepsy.Role of serum- and glucocorticoid-inducible kinases in stroke.iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases.Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel.Origins of Phantom Limb Pain.Differential Inhibition of Nav1.7 and Neuropathic Pain by Hybridoma-Produced and Recombinant Monoclonal Antibodies that Target Nav1.7 : Differential activities of Nav1.7-targeting monoclonal antibodies.Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice.Signatures of Altered Gene Expression in Dorsal Root Ganglia of a Fabry Disease Mouse Model.Posttranslational Modification of Sodium Channels.Wogonin inhibits LPS-induced inflammatory responses in rat dorsal root ganglion neurons via inhibiting TLR4-MyD88-TAK1-mediated NF-κB and MAPK signaling pathway.CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain

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P2860

Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain.

http://www.wikidata.org/entity/Q34351740

description

2013 nî lūn-bûn

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2013 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2013 թվականի հունիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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Dysregulation of voltage-gated ...... e NEDD4-2 in neuropathic pain.

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Dysregulation of voltage-gated ...... e NEDD4-2 in neuropathic pain.

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Dysregulation of voltage-gated ...... e NEDD4-2 in neuropathic pain.

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Dysregulation of voltage-gated ...... e NEDD4-2 in neuropathic pain.

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Dysregulation of voltage-gated ...... e NEDD4-2 in neuropathic pain.

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Dysregulation of voltage-gated ...... e NEDD4-2 in neuropathic pain.

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Dysregulation of voltage-gated ...... e NEDD4-2 in neuropathic pain.

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Dysregulation of voltage-gated ...... e NEDD4-2 in neuropathic pain.

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Dysregulation of voltage-gated ...... e NEDD4-2 in neuropathic pain.

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Bernard L Schneider

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Chris Towne

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Cédric J Laedermann

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Guylène Kirschmann

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Hugues Abriel

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Isabelle Chang

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Isabelle Decosterd

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Marie Pertin

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Matthieu Cachemaille

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Maxime Albesa

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P2860

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain

Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

The crystal structure of a voltage-gated sodium channel

SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

An SCN9A channelopathy causes congenital inability to experience pain

A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons

A role of the ubiquitin-proteasome system in neuropathic pain

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10.1172/JCI68996

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7

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23778145

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neuropathic pain

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3696561

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