3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria

3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria

Item
http://www.wikidata.org/entity/Q34352165
Resistance to antibiotics targeted to the bacterial cell wallChallenges of antibacterial discoveryLucY: A Versatile New Fluorescent Reporter ProteinEvaluation of the metS and murB loci for antibiotic discovery using targeted antisense RNA expression analysis in Bacillus anthracis.Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development.Targeting the formation of the cell wall core of M. tuberculosis.Cytoplasmic steps of peptidoglycan biosynthesis.Development of a one-pot assay for screening and identification of Mur pathway inhibitors in Mycobacterium tuberculosis.Peptidoglycan biosynthesis machinery: a rich source of drug targets.Screening strategies for discovery of antibacterial natural products.Inhibitors targeting on cell wall biosynthesis pathway of MRSA.Identification of hotspot regions of MurB oxidoreductase enzyme using homology modeling, molecular dynamics and molecular docking techniques.Identification of druggable targets for Acinetobacter baumannii via subtractive genomics and plausible inhibitors for MurA and MurB.Computed insight into a peptide inhibitor preventing the induced fit mechanism of MurA enzyme from Pseudomonas aeruginosa.Feglymycin is an inhibitor of the enzymes MurA and MurC of the peptidoglycan biosynthesis pathway.A homogeneous, high-throughput-compatible, fluorescence intensity-based assay for UDP-N-acetylenolpyruvylglucosamine reductase (MurB) with nanomolar product detection.
P2860

3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria

Item
http://www.wikidata.org/entity/Q34352165
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
@ast
3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
@en
3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
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type
label
3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
@ast
3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
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3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
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prefLabel
3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
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3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
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3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
3,5-dioxopyrazolidines, novel ...... against gram-positive bacteria
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P2093
P2860
P304
P31
P356
10.1128/AAC.50.2.556-564.2006
P407
P433
P478
P577
P698
P921
P932