The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization.
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Purification of two distinct proteins of approximate Mr 80,000 from human epithelial cells and identification as proper substrates for protein kinase CPurification and characterization of a brain-specific protein kinase C substrate, neurogranin (p17). Identification of a consensus amino acid sequence between neurogranin and neuromodulin (GAP43) that corresponds to the protein kinase C phosphorylatA mouse brain cDNA encodes a novel protein with the protein kinase C phosphorylation site domain common to MARCKSMARCKS is a natively unfolded protein with an inaccessible actin-binding site: evidence for long-range intramolecular interactionsHemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelleElectrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins.Biphasic modulation of protein kinase C and enhanced cell toxicity by amyloid beta peptide and anoxia in neuronal cultures.Cloning and molecular characterization of the murine macrophage "68-kDa" protein kinase C substrate and its regulation by bacterial lipopolysaccharidePhosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II.Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate.Brain protein kinase C phosphorylating poly(arginine,serine) or lamin B is stimulated by anions and by an activator purified from bovine serum albumin preparations.Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminalsDecreased susceptibility of a 70-kDa protein to cathepsin L after phosphorylation by protein kinase C.Molecular cloning, characterization, and expression of a cDNA encoding the "80- to 87-kDa" myristoylated alanine-rich C kinase substrate: a major cellular substrate for protein kinase C.Phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) protein is associated with bovine luteal oxytocin exocytosis.Phosphorylation reverses the membrane association of peptides that correspond to the basic domains of MARCKS and neuromodulin.1,25-Dihydroxyvitamin D3 and 12-O-tetradecanoyl phorbol 13-acetate cause differential activation of Ca(2+)-dependent and Ca(2+)-independent isoforms of protein kinase C in rat colonocytes.Evidence that v-src and v-fps gene products use a protein kinase C-mediated pathway to induce expression of a transformation-related geneMyristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains.Cross-talk unfolded: MARCKS proteins.MARCKS deficiency in mice leads to abnormal brain development and perinatal death.The mitogenic signaling pathway but not the plasminogen activator-inducing pathway of basic fibroblast growth factor is mediated through protein kinase C in fetal bovine aortic endothelial cells.Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia.Neuropeptides as cellular growth factors: role of multiple signalling pathways.Functional role of the interaction between polysialic acid and myristoylated alanine-rich C kinase substrate at the plasma membraneAbnormal protein kinase C down regulation and reduced substrate levels in non-phorbol ester-responsive 3T3-TNR9 cells.A major myristylated substrate of protein kinase C and protein kinase C itself are differentially regulated during murine B- and T-lymphocyte development and activation.MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma.Regulation of mucin secretion and inflammation in asthma: a role for MARCKS protein?Molecular determinants of the myristoyl-electrostatic switch of MARCKS.Functional characterization of the tumor-suppressor MARCKS in colorectal cancer and its association with survival.Stimulus-dependent phosphorylation of MacMARCKS, a protein kinase C substrate, in nerve termini and PC12 cells.Phosphorylation of p90 and p52 in response to phorbol-esters in Swiss/3T3 cells overexpressing protein kinase C-alpha.The protein kinase C (PKC) substrate GAP-43 is already expressed in neural precursor cells, colocalizes with PKCeta and binds calmodulin.1,25-Dihydroxyvitamin D3 stimulates expression and translocation of protein kinase Calpha and Cdelta via a nongenomic mechanism and rapidly induces phosphorylation of a 33-kDa protein in acute promyelocytic NB4 cells.Multisite phosphorylation of the 80 kDa (MARCKS) protein kinase C substrate in C3H/10T1/2 fibroblasts. Quantitative analysis of individual sites by solid-phase microsequencing.Purification and internal amino acid sequence of the 80 kDa protein kinase C substrate from Swiss 3T3 fibroblasts. Homology with substrates from brain.Protein kinase C mediates cholinergically regulated protein phosphorylation in a Cl(-)-secreting epithelium.Mitogen-induced phosphorylation of human B-lymphocyte proteins. Relationship to protein kinase C activation.Evidence for a non-myristoylated pool of the 80 kDa protein kinase C substrate of rat brain.
P2860
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P2860
The 87-kDa protein, a major specific substrate for protein kinase C: purification from bovine brain and characterization.
description
1987 nî lūn-bûn
@nan
1987 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
The 87-kDa protein, a major sp ...... ne brain and characterization.
@ast
The 87-kDa protein, a major sp ...... ne brain and characterization.
@en
The 87-kDa protein, a major sp ...... ne brain and characterization.
@nl
type
label
The 87-kDa protein, a major sp ...... ne brain and characterization.
@ast
The 87-kDa protein, a major sp ...... ne brain and characterization.
@en
The 87-kDa protein, a major sp ...... ne brain and characterization.
@nl
prefLabel
The 87-kDa protein, a major sp ...... ne brain and characterization.
@ast
The 87-kDa protein, a major sp ...... ne brain and characterization.
@en
The 87-kDa protein, a major sp ...... ne brain and characterization.
@nl
P2860
P356
P1476
The 87-kDa protein, a major sp ...... ne brain and characterization.
@en
P2093
P2860
P304
P356
10.1073/PNAS.84.20.7046
P407
P577
1987-10-01T00:00:00Z