Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation.
about
Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleasesA human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group MThe hSNM1 protein is a DNA 5'-exonucleaseThe Chemical Biology of Human Metallo-β-Lactamase Fold ProteinsFunction of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal-Hreidarsson syndromeCellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insightsApollo contributes to G overhang maintenance and protects leading-end telomeresSNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repairEndogenous hSNM1B/Apollo interacts with TRF2 and stimulates ATM in response to ionizing radiation.The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegansDNA interstrand crosslink repair in mammalian cells: step by step.The multifunctional SNM1 gene family: not just nucleasesNew mutations in the ATM gene and clinical data of 25 AT patients.Snm1-deficient mice exhibit accelerated tumorigenesis and susceptibility to infection.The telomeric protein SNM1B/Apollo is required for normal cell proliferation and embryonic development.Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair.Snm1B interacts with PSF2.hSnm1B is a novel telomere-associated protein.Nucleases of the metallo-beta-lactamase family and their role in DNA and RNA metabolism.The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability.Snm1B/Apollo functions in the Fanconi anemia pathway in response to DNA interstrand crosslinks.Mammalian ChlR1 has a role in heterochromatin organization.Contributions of DNA interstrand cross-links to aging of cells and organisms.Repair of DNA interstrand cross-links during S phase of the mammalian cell cycle.Telomere dysfunction in human bone marrow failure syndromes.Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair.DNA Replication Origins and Fork Progression at Mammalian TelomeresSNM1B/Apollo in the DNA damage response and telomere maintenanceMouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair.The protein hSnm1B is stabilized when bound to the telomere-binding protein TRF2.A prototypical Fanconi anemia pathway in lower eukaryotes?Pso2 (SNM1) is a DNA structure-specific endonuclease.Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links.The structures of the SNM1A and SNM1B/Apollo nuclease domains reveal a potential basis for their distinct DNA processing activities.Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.An in vivo analysis of MMC-induced DNA damage and its repair.[Dyskeratosis congenita: short telomeres are not the rule].
P2860
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P2860
Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Human SNM1B is required for no ...... agents and ionizing radiation.
@ast
Human SNM1B is required for no ...... agents and ionizing radiation.
@en
Human SNM1B is required for no ...... agents and ionizing radiation.
@nl
type
label
Human SNM1B is required for no ...... agents and ionizing radiation.
@ast
Human SNM1B is required for no ...... agents and ionizing radiation.
@en
Human SNM1B is required for no ...... agents and ionizing radiation.
@nl
prefLabel
Human SNM1B is required for no ...... agents and ionizing radiation.
@ast
Human SNM1B is required for no ...... agents and ionizing radiation.
@en
Human SNM1B is required for no ...... agents and ionizing radiation.
@nl
P2860
P356
P1433
P1476
Human SNM1B is required for no ...... agents and ionizing radiation.
@en
P2093
Martin Digweed
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207895
P407
P577
2004-11-01T00:00:00Z
P5875
P6179
1032261616