The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis. - Wikidata - awgldk - TriplyDB

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis.

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis.

http://www.wikidata.org/entity/Q34360138

about

Chemokines and Chemokine Receptors in the Development of Lupus Nephritis Decoding the Matrix: Instructive Roles of Proteoglycan Receptors Graft rejection - endogenous or allogeneic?Biological interplay between proteoglycans and their innate immune receptors in inflammation Insights into the key roles of proteoglycans in breast cancer biology and translational medicine Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21 The pathogenesis, diagnosis and treatment of lupus nephritis.Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury.Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology Serum autoantibodies in pristane induced lupus are regulated by neutrophil gelatinase associated lipocalin Soluble biglycan induces the production of ICAM-1 and MCP-1 in human aortic valve interstitial cells through TLR2/4 and the ERK1/2 pathway.Soluble biglycan as a biomarker of inflammatory renal diseases.Toll-like receptor 2 is required for autoantibody production and development of renal disease in pristane-induced lupus.Toll-like receptor 2 or toll-like receptor 4 deficiency does not modify lupus in MRLlpr mice Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation.Since there are PAMPs and DAMPs, there must be SAMPs? Glycan “self-associated molecular patterns” dampen innate immunity, but pathogens can mimic them.Escape from X inactivation varies in mouse tissues.Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti-inflammatory activities in vitro and in vivo The interplay of extracellular matrix and microbiome in urothelial bladder cancer.A comparative evaluation of the small leucine-rich proteoglycans of pathological human intervertebral discs.The small leucine-rich proteoglycan, biglycan, is highly expressed in adipose tissue of Psammomys obesus and is associated with obesity and type 2 diabetes Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance.Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation.Decreased body fat, elevated plasma transforming growth factor-β levels, and impaired BMP4-like signaling in biglycan-deficient mice.Evasion and interactions of the humoral innate immune response in pathogen invasion, autoimmune disease, and cancer Decorin: a guardian from the matrix The small leucine-rich repeat proteoglycans in tissue repair and atherosclerosis Cyclin-dependent kinase inhibitor Cdkn2c deficiency promotes B1a cell expansion and autoimmunity in a mouse model of lupus.Soluble biglycan: a potential mediator of cartilage degradation in osteoarthritis Biglycan: a multivalent proteoglycan providing structure and signals An introduction to proteoglycans and their localization Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B.Enhanced biglycan gene expression in the adipose tissues of obese women and its association with obesity-related genes and metabolic parameters.CXCL13 is elevated in Sjögren's syndrome in mice and humans and is implicated in disease pathogenesis Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants.Immunopathology of lupus nephritis.Topographical changes in extracellular matrix: Activation of TLR4 signaling and solid tumor progression.Beyond tissue injury-damage-associated molecular patterns, toll-like receptors, and inflammasomes also drive regeneration and fibrosis.CXCL13 as a new biomarker of systemic lupus erythematosus and lupus nephritis - from bench to bedside?

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The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis.

http://www.wikidata.org/entity/Q34360138

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The proteoglycan biglycan regu ...... avates murine lupus nephritis.

@ast

The proteoglycan biglycan regu ...... avates murine lupus nephritis.

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The proteoglycan biglycan regu ...... avates murine lupus nephritis.

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type

label

The proteoglycan biglycan regu ...... avates murine lupus nephritis.

@ast

The proteoglycan biglycan regu ...... avates murine lupus nephritis.

@en

The proteoglycan biglycan regu ...... avates murine lupus nephritis.

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prefLabel

The proteoglycan biglycan regu ...... avates murine lupus nephritis.

@ast

The proteoglycan biglycan regu ...... avates murine lupus nephritis.

@en

The proteoglycan biglycan regu ...... avates murine lupus nephritis.

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Journal of Clinical Investigation

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The proteoglycan biglycan regu ...... avates murine lupus nephritis.

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P2093

Andrea Babelova

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Jinyang Zeng-Brouwers

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Josef Pfeilschifter

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Kristin Moreth

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Liliana Schaefer

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Marian F Young

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Norbert Gretz

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Rebekka Brodbeck

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Roland M Schaefer

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Tilmann Spieker

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P2860

Borrelia garinii induces CXCL13 production in human monocytes through Toll-like receptor 2

BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection

B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumoniae

A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1

B1b lymphocytes confer T cell-independent long-lasting immunity

Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen

Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation

Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

Lymphatic neoangiogenesis in human kidney transplants is associated with immunologically active lymphocytic infiltrates.

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4251-4272

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10.1172/JCI42213

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12

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120

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2010-11-15T00:00:00Z

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21084753

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2993585

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