Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation.
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Messenger RNAs localized to distal projections of human stem cell derived neurons.The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP AssemblyWhole transcriptome profiling reveals the RNA content of motor axonsDeficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.Transcriptional enhancement of Smn levels in motoneurons is crucial for proper axon morphology in zebrafish.Developing therapies for spinal muscular atrophy.Advances in understanding the role of disease-associated proteins in spinal muscular atrophy.ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models.Differential roles of α-, β-, and γ-actin in axon growth and collateral branch formation in motoneurons.Spatially and temporally regulating translation via mRNA-binding proteins in cellular and neuronal function.Developmental regulation of SMN expression: pathophysiological implications and perspectives for therapy development in spinal muscular atrophy.Expanding Axonal Transcriptome Brings New Functions for Axonally Synthesized Proteins in Health and Disease.Optimized Whole Transcriptome Profiling of Motor Axons.To the end of the line: Axonal mRNA transport and local translation in health and neurodegenerative disease.RNA-binding proteins in neurodegeneration: mechanisms in aggregate.Axonal localization of neuritin/CPG15 mRNA is limited by competition for HuD binding.Motor neuronal repletion of the NMJ organizer, Agrin, modulates the severity of the spinal muscular atrophy disease phenotype in model mice.mRNP assembly, axonal transport, and local translation in neurodegenerative diseases.hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons.Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophyUnraveling the Pathways to Neuronal Homeostasis and Disease: Mechanistic Insights into the Role of RNA-Binding Proteins and Associated Factors
P2860
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P2860
Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Subcellular transcriptome alte ...... d presynaptic differentiation.
@ast
Subcellular transcriptome alte ...... d presynaptic differentiation.
@en
Subcellular transcriptome alte ...... d presynaptic differentiation.
@nl
type
label
Subcellular transcriptome alte ...... d presynaptic differentiation.
@ast
Subcellular transcriptome alte ...... d presynaptic differentiation.
@en
Subcellular transcriptome alte ...... d presynaptic differentiation.
@nl
prefLabel
Subcellular transcriptome alte ...... d presynaptic differentiation.
@ast
Subcellular transcriptome alte ...... d presynaptic differentiation.
@en
Subcellular transcriptome alte ...... d presynaptic differentiation.
@nl
P2093
P2860
P356
P1433
P1476
Subcellular transcriptome alte ...... d presynaptic differentiation.
@en
P2093
Michael Briese
Michael Glinka
Susanne Kneitz
P2860
P304
P356
10.1261/RNA.047373.114
P407
P577
2014-09-22T00:00:00Z