Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
about
Suppression of the Arboviruses Dengue and Chikungunya Using a Dual-Acting Group-I Intron Coupled with Conditional Expression of the Bax C-Terminal DomainTargeting of highly conserved Dengue virus sequences with anti-Dengue virus trans-splicing group I introns.Effective suppression of dengue virus using a novel group-I intron that induces apoptotic cell death upon infection through conditional expression of the Bax C-terminal domainAn in vivo selection method to optimize trans-splicing ribozymesDesign and Experimental Evolution of trans-Splicing Group I Intron Ribozymes.Variables and strategies in development of therapeutic post-transcriptional gene silencing agentsSpliceozymes: ribozymes that remove introns from pre-mRNAs in trans.Computational prediction of efficient splice sites for trans-splicing ribozymes.Disruption of dengue virus transmission by mosquitoes.Natural and engineered nucleic acids as tools to explore biology.Gene therapy progress and prospects: reprograming gene expression by trans-splicing.Convergent evolution of twintron-like configurations: One is never enough.Modulating the expression of disease genes with RNA-based therapy.Low selection pressure aids the evolution of cooperative ribozyme mutations in cellsGenetic strategies for the treatment of sickle cell anaemia.Specific and Efficient Regression of Cancers Harboring KRAS Mutation by Targeted RNA Replacement.RNA Trans-Splicing Targeting Endogenous β-Globin Pre-Messenger RNA in Human Erythroid Cells.Trans-splicing group I intron targeting hepatitis C virus IRES mediates cell death upon viral infection in Huh7.5 cells.Intracellular efficacy of tumor-targeting group I intron-based trans-splicing ribozyme.Self-splicing of a group I intron reveals partitioning of native and misfolded RNA populations in yeast.In vivo excision of a single targeted nucleotide from an mRNA by a trans excision-splicing ribozymeTrans-splicing with the group I intron ribozyme from Azoarcus.In vivo evolution of a catalytic RNA couples trans-splicing to translation.Cancer-selective induction of cytotoxicity by tissue-specific expression of targeted trans-splicing ribozyme.Selective and efficient retardation of cancers expressing cytoskeleton-associated protein 2 by targeted RNA replacement.Heterodimerization of Group I Ribozymes Enabling Exon Recombination through Pairs of Cooperative trans-Splicing Reactions.
P2860
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P2860
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@ast
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@en
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@nl
type
label
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@ast
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@en
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@nl
prefLabel
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@ast
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@en
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@nl
P2093
P2860
P356
P1433
P1476
Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.
@en
P2093
Bruce A Sullenger
Jonghoe Byun
Meredith Long
P2860
P304
P356
10.1261/RNA.5450203
P407
P577
2003-10-01T00:00:00Z