Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
about
Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effectsRDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA.Inositol hexakisphosphate is bound in the ADAR2 core and required for RNA editingModulation of ADAR1 editing activity by Z-RNA in vitro.New Insights into the Biological Role of Mammalian ADARs; the RNA Editing ProteinsThe Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor GrooveStructural conservation of an ancient tRNA sensor in eukaryotic glutaminyl-tRNA synthetaseThe Structure of Yeast Glutaminyl-tRNA Synthetase and Modeling of Its Interaction with tRNAFunctions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human DiseasesRNA-binding proteins: modular design for efficient functionDimerization of ADAR2 is mediated by the double-stranded RNA binding domainAn efficient system for selectively altering genetic information within mRNAs.RNA binding-independent dimerization of adenosine deaminases acting on RNA and dominant negative effects of nonfunctional subunits on dimer functions.Potent and selective inhibition of A-to-I RNA editing with 2'-O-methyl/locked nucleic acid-containing antisense oligoribonucleotides.Adenosine deaminases acting on RNA, RNA editing, and interferon action.Substrate-dependent contribution of double-stranded RNA-binding motifs to ADAR2 functionPredicting sites of ADAR editing in double-stranded RNA.Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing.Mechanisms of dendritic mRNA transport and its role in synaptic tagging.A transition state analogue for an RNA-editing reaction.A Fluorescent Adenosine Analogue as a Substrate for an A-to-I RNA Editing Enzyme.Duplex RNA-binding enzymes: headliners from neurobiology, virology, and development.Nucleoside analog studies indicate mechanistic differences between RNA-editing adenosine deaminases.Mechanistic insights into editing-site specificity of ADARs.Large-scale overexpression and purification of ADARs from Saccharomyces cerevisiae for biophysical and biochemical studies.Dynamic regulation of RNA editing of ion channels and receptors in the mammalian nervous system.Synthesis and evaluation of an RNA editing substrate bearing 2'-deoxy-2'-mercaptoadenosine.RNA-Seq analysis identifies a novel set of editing substrates for human ADAR2 present in Saccharomyces cerevisiae.Site-selective versus promiscuous A-to-I editing.Activity regulation of adenosine deaminases acting on RNA (ADARs).How do ADARs bind RNA? New protein-RNA structures illuminate substrate recognition by the RNA editing ADARs.A zipcode unzippedControlling the Editor: The Many Roles of RNA-Binding Proteins in Regulating A-to-I RNA Editing.A protein-protein interaction underlies the molecular basis for substrate recognition by an adenosine-to-inosine RNA-editing enzyme
P2860
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P2860
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
name
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@ast
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@en
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@nl
type
label
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@ast
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@en
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@nl
prefLabel
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@ast
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@en
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@nl
P2093
P2860
P356
P1433
P1476
Evidence for auto-inhibition by the N terminus of hADAR2 and activation by dsRNA binding.
@en
P2093
Arunth T Lingam
Brenda L Bass
Mark R Macbeth
P2860
P304
P356
10.1261/RNA.7920904
P407
P577
2004-10-01T00:00:00Z