MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma. - Wikidata - awgldk - TriplyDB

MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma.

MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma.

http://www.wikidata.org/entity/Q34366539

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MEF2 transcription factors: developmental regulators and emerging cancer genes The genetic landscape of diffuse large B-cell lymphoma Chromatin signatures of cancer Novel drug targets for personalized precision medicine in relapsed/refractory diffuse large B-cell lymphoma: a comprehensive review ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state Role of MYC in B Cell Lymphomagenesis.Diffuse large B-cell lymphoma: can genomics improve treatment options for a curable cancer?The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness.Cell-cycle reprogramming for PI3K inhibition overrides a relapse-specific C481S BTK mutation revealed by longitudinal functional genomics in mantle cell lymphoma Pattern of MEF2B expression in lymphoid tissues and in malignant lymphomas.Dynamics of B cells in germinal centres.Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.Tacrolimus restores podocyte injury and stabilizes the expression of Cabin1 in 5/6 nephrectomized rats.Genetic lesions in diffuse large B-cell lymphomas Identification of MEF2B, EBF1, and IL6R as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte Survival Targetable genetic features of primary testicular and primary central nervous system lymphomas.Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease.Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development.MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation Phase 2 study of panobinostat with or without rituximab in relapsed diffuse large B-cell lymphoma.Epigenetic and Glucocorticoid Receptor-Mediated Regulation of Glutathione Peroxidase 3 in Lung Cancer Cells Synergistic activity of Card11 mutant and Bcl6 in the development of diffuse large B-cell lymphoma in a mouse model.Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice.Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma.The genetic basis of diffuse large B-cell lymphoma.Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesis.Activating somatic mutations in diffuse large B-cell lymphomas: lessons from next generation sequencing and key elements in the precision medicine era.Precision therapy for lymphoma--current state and future directions.The molecular pathogenesis of B-cell non-Hodgkin lymphoma.Genetic landscape and deregulated pathways in B-cell lymphoid malignancies.Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma.Diagnostic and predictive biomarkers for lymphoma diagnosis and treatment in the era of precision medicine.BCL6--regulated by AhR/ARNT and wild-type MEF2B--drives expression of germinal center markers MYBL1 and LMO2.Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development Systematic discovery of linear binding motifs targeting an ancient protein interaction surface on MAP kinases.Mutational profiling of acute lymphoblastic leukemia with testicular relapse.It's a long way to the top (if you want to personalize immunotherapy)High-risk follicular lymphomas harbour more somatic mutations including those in the AID-motif BCL6 as a therapeutic target for lymphoma.

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MEF2B mutations lead to deregulated expression of the oncogene BCL6 in diffuse large B cell lymphoma.

http://www.wikidata.org/entity/Q34366539

description

2013 nî lūn-bûn

@nan

2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի օգոստոսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@ast

MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@en

MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@nl

type

label

MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@ast

MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@en

MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@nl

prefLabel

MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@ast

MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@en

MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@nl

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Nature Immunology

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MEF2B mutations lead to deregu ...... diffuse large B cell lymphoma.

@en

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Andrea Califano

http://www.w3.org/2001/XMLSchema#string

Carol Y Ying

http://www.w3.org/2001/XMLSchema#string

David Dominguez-Sola

http://www.w3.org/2001/XMLSchema#string

Ivo C Lorenz

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Katia Basso

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Melissa Fabi

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Mukesh Bansal

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Riccardo Dalla-Favera

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Shafinaz Hussein

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P2860

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers

BCL-6 protein is expressed in germinal-center B cells

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Transcriptional analysis of the B cell germinal center reaction

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity

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1084-1092

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scholarly article

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10.1038/NI.2688

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10

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14

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Laura Pasqualucci

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2013-08-25T00:00:00Z

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256100894

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23974956

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3954820

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