Small molecule antagonists for CXCR2 and CXCR1 inhibit human colon cancer liver metastases. - Wikidata - awgldk - TriplyDB

Small molecule antagonists for CXCR2 and CXCR1 inhibit human colon cancer liver metastases.

Small molecule antagonists for CXCR2 and CXCR1 inhibit human colon cancer liver metastases.

http://www.wikidata.org/entity/Q34367591

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The Role of Chemokines in Promoting Colorectal Cancer Invasion/Metastasis Chemokine/chemokine receptor pair CCL20/CCR6 in human colorectal malignancy: An overview Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agents CXC chemokines and chemokine receptors in gastric cancer: from basic findings towards therapeutic targeting The CXCL8-CXCR1/2 pathways in cancer ABCB5 maintains melanoma-initiating cells through a proinflammatory cytokine signaling circuit CXCR2 signaling regulates KRAS(G¹²D)-induced autocrine growth of pancreatic cancer.Blockade of Neutrophil's Chemokine Receptors CXCR1/2 Abrogate Liver Damage in Acute-on-Chronic Liver Failure.Single cells from human primary colorectal tumors exhibit polyfunctional heterogeneity in secretions of ELR+ CXC chemokines Overexpression of CXCR2 predicts poor prognosis in patients with colorectal cancer The IL-8/CXCR1 axis is associated with cancer stem cell-like properties and correlates with clinical prognosis in human pancreatic cancer cases.The role of chemoattractant receptors in shaping the tumor microenvironment.The emerging role of CXC chemokines and their receptors in cancer.Targeting IL-8 in colorectal cancer.Influence of the CXCL1 rs4074 A allele on alcohol induced cirrhosis and HCC in patients of European descent.The prognostic significance of CXCL1 hypersecretion by human colorectal cancer epithelia and myofibroblasts Role of chemokine receptor CXCR2 expression in mammary tumor growth, angiogenesis and metastasis.The prognostic value of CXC-chemokine receptor 2 (CXCR2) in gastric cancer patients.Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery Boronic acid-containing aminopyridine- and aminopyrimidinecarboxamide CXCR1/2 antagonists: Optimization of aqueous solubility and oral bioavailability.CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.Expression of C-X-C chemokine receptor types 1/2 in patients with gastric carcinoma: Clinicopathological correlations and significance Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil Berberine suppresses migration of MCF-7 breast cancer cells through down-regulation of chemokine receptors.Polyisoprenylated methylated protein methyl esterase is both sensitive to curcumin and overexpressed in colorectal cancer: implications for chemoprevention and treatment.CXCL8, IL-1β and sCD200 are pro-inflammatory cytokines and their levels increase in the circulation of breast carcinoma patients.Silencing of CXCR2 and CXCR7 protects against esophageal cancer Level of TNF-related apoptosis-inducing-ligand and CXCL8 correlated with 2-[18F]Fluoro-2-deoxy-D-glucose uptake in anti-VEGF treated colon cancers.miR-940 Suppresses Tumor Cell Invasion and Migration via Regulation of CXCR2 in Hepatocellular Carcinoma.Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells.Molecular mechanisms of liver metastasis.The Chemokine CXCL8 in Carcinogenesis and Drug Response.Rationale and Means to Target Pro-Inflammatory Interleukin-8 (CXCL8) Signaling in Cancer.CXCR2 modulators: a patent review (2009 - 2013).The colon cancer stem cell microenvironment holds keys to future cancer therapy.The CXCR1/2 Pathway: Involvement in Diabetes Pathophysiology and Potential Target for T1D Interventions.Neutrophils: important contributors to tumor progression and metastasis.Analysis of Chemokine Receptor Gene Expression in Esophageal Cancer Cells Compared with Breast Cancer with Insights into Metastasis.Autocrine control of MIP-2 secretion from metastatic breast cancer cells is mediated by CXCR2: a mechanism for possible resistance to CXCR2 antagonists.The chemokine receptors CXCR1 and CXCR2 regulate oral cancer cell behaviour.

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P2860

Small molecule antagonists for CXCR2 and CXCR1 inhibit human colon cancer liver metastases.

http://www.wikidata.org/entity/Q34367591

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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name

Small molecule antagonists for ...... colon cancer liver metastases.

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Small molecule antagonists for ...... colon cancer liver metastases.

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Small molecule antagonists for ...... colon cancer liver metastases.

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Small molecule antagonists for ...... colon cancer liver metastases.

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Small molecule antagonists for ...... colon cancer liver metastases.

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Small molecule antagonists for ...... colon cancer liver metastases.

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Small molecule antagonists for ...... colon cancer liver metastases.

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Small molecule antagonists for ...... colon cancer liver metastases.

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Small molecule antagonists for ...... colon cancer liver metastases.

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Aihua Li

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Michelle L Varney

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Rakesh K Singh

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Richard Bond

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Rosemary Mayer-Ezell

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P2860

The Duffy antigen/receptor for chemokines (DARC) is expressed in endothelial cells of Duffy negative individuals who lack the erythrocyte receptor

Cancer statistics, 2010

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

International union of pharmacology. XXII. Nomenclature for chemokine receptors

Tumor metastasis: mechanistic insights and clinical challenges

The biology of chemokines and their receptors

The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity.

Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor

IL-8 expression in malignant melanoma: implications in growth and metastasis.

Development of dendritic-cell based prostate cancer vaccine.

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