Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor.
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The AP-2 family of transcription factorsZfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress responseInhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor proteinTransforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1GAS41 interacts with transcription factor AP-2beta and stimulates AP-2beta-mediated transactivationFragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancerTargeted deletion of Wwox reveals a tumor suppressor functionProof of concept for microarray-based detection of DNA-binding oncogenes in cell extractsHYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer ResponsePleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer CellsThe WWOX tumor suppressor is essential for postnatal survival and normal bone metabolismCell death or survival promoted by alternative isoforms of ErbB4Aurora-A interacts with AP-2α and down regulates its transcription activityProline-rich sequence recognition: I. Marking GYF and WW domain assembly sites in early spliceosomal complexes.Generation and characterization of mice carrying a conditional allele of the Wwox tumor suppressor geneWwox-Brca1 interaction: role in DNA repair pathway choiceIdentification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genesTFAP2B overexpression contributes to tumor growth and a poor prognosis of human lung adenocarcinoma through modulation of ERK and VEGF/PEDF signalingWWOX gene restoration prevents lung cancer growth in vitro and in vivoWWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.Conditional Wwox deletion in mouse mammary gland by means of two Cre recombinase approaches.Oncosuppressor proteins of fragile sites are reduced in cervical cancer.WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response.Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.WWOX suppresses prostate cancer cell progression through cyclin D1-mediated cell cycle arrest in the G1 phase.Structural insights into the functional versatility of WW domain-containing oxidoreductase tumor suppressor.Activating enhancer-binding protein-2α induces cyclooxygenase-2 expression and promotes nasopharyngeal carcinoma growth.A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex developmentWW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β.Protein inhibitor of activated STAT3 (PIAS3) protein promotes SUMOylation and nuclear sequestration of the intracellular domain of ErbB4 protein.Biophysical basis of the binding of WWOX tumor suppressor to WBP1 and WBP2 adaptorsThe ectopic expression of BRCA1 is associated with genesis, progression, and prognosis of breast cancer in young patientsActivator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review.WWOX in biological control and tumorigenesis.Alteration of WWOX in human cancer: a clinical view.Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma.Regulation of cell signaling and apoptosis by tumor suppressor WWOX.Roles of the WWOX in pathogenesis and endocrine therapy of breast cancer.Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductaseA nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells.
P2860
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P2860
Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Physical and functional intera ...... P-2gamma transcription factor.
@ast
Physical and functional intera ...... P-2gamma transcription factor.
@en
Physical and functional intera ...... P-2gamma transcription factor.
@nl
type
label
Physical and functional intera ...... P-2gamma transcription factor.
@ast
Physical and functional intera ...... P-2gamma transcription factor.
@en
Physical and functional intera ...... P-2gamma transcription factor.
@nl
prefLabel
Physical and functional intera ...... P-2gamma transcription factor.
@ast
Physical and functional intera ...... P-2gamma transcription factor.
@en
Physical and functional intera ...... P-2gamma transcription factor.
@nl
P2093
P1433
P1476
Physical and functional intera ...... P-2gamma transcription factor.
@en
P2093
Alexey Palamarchuk
Juan J Herrero
Rami I Aqeilan
Ronald J Weigel
Yuri Pekarsky
P304
P356
10.1158/0008-5472.CAN-04-2055
P407
P577
2004-11-01T00:00:00Z