Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids.
about
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signalingIdentification of a novel extracellular cation-sensing G-protein-coupled receptorGPRC6A mediates the non-genomic effects of steroids.Hypercalcaemic and hypocalcaemic conditions due to calcium-sensing receptor mutationsThe Calcium-Sensing Receptor and Integrins in Cellular Differentiation and MigrationThe L-Cell in Nutritional Sensing and the Regulation of AppetiteMinireview: Nutrient sensing by G protein-coupled receptorsRecent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1GPRC6A mediates responses to osteocalcin in β-cells in vitro and pancreas in vivoPresynaptic external calcium signaling involves the calcium-sensing receptor in neocortical nerve terminalsGPRC6A null mice exhibit osteopenia, feminization and metabolic syndromeThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsCommon ligands of G-protein-coupled receptors and arginine-utilizing enzymes.A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacids.Minireview: the intimate link between calcium sensing receptor trafficking and signaling: implications for disorders of calcium homeostasis.The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site.Chaperoning G protein-coupled receptors: from cell biology to therapeuticsLysine and arginine reduce the effects of cerebral ischemic insults and inhibit glutamate-induced neuronal activity in ratsGPRC6A regulates prostate cancer progressionThe use of Xenopus oocytes in drug screening.The calcium-sensing receptor and related diseases.Endocrine regulation of male fertility by the skeleton.L-cysteine suppresses ghrelin and reduces appetite in rodents and humansAncestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptors.Impaired osteoblast function in GPRC6A null mice.Known regulators of nitric oxide synthase and arginase are agonists at the human G-protein-coupled receptor GPRC6A.The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.The role of osteocalcin in human glucose metabolism: marker or mediator?Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin VariantsPharmacological characterization of mouse GPRC6A, an L-alpha-amino-acid receptor modulated by divalent cations.Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.Peripheral neural targets in obesityMolecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators.Orphan GPCRs and neuromodulation.GPRC6a is not required for the effects of a high-protein diet on body weight in miceGPRC6A mediates the effects of L-arginine on insulin secretion in mouse pancreatic islets.Evidence for Osteocalcin Binding and Activation of GPRC6A in β-CellsNew paradigms in GPCR drug discovery.L-arginine promotes gut hormone release and reduces food intake in rodents.Searching for additional endocrine functions of the skeleton: genetic approaches and implications for therapeutics.
P2860
Q24294906-D4AD1CF5-9265-4501-B168-FC044D59D921Q24548217-9A8470DF-586A-44E8-BDB1-9FD64B8A2301Q24629789-AB969C24-5751-4A27-AF88-CA802949A33CQ24648139-BB343964-EECA-487F-BB44-2AB9ED4B18D3Q26746018-F9256DE4-3E92-4F22-8762-F67183E6B035Q26799942-357438A9-79A8-4D9A-ADA6-9F13BB1F6DFAQ26864827-AE59D081-C4C5-46C9-9367-10ACD99933E0Q28068298-9367883B-FBF9-4F02-A153-02D89797A870Q28307776-E9A1D651-955C-4383-8842-3FAEB1E6731BQ28749489-8797E50E-58F1-4A5C-A946-15DBFA25E26AQ30440683-8D7D3D40-512D-4C6D-9B8A-EF93859F8997Q30486707-F1E94E33-1F49-46B2-AF22-7566B682576FQ31032757-F35D71CA-6522-4DFF-8AF2-30436C9BC2AEQ33450644-EFFC0787-141D-4FB0-821A-0889CE7E849BQ33636300-860C5851-C575-454D-B1BC-6E2EF591568DQ33683166-8B463351-63E3-4620-80DB-0CE129EE5A58Q33927508-9E32810C-CD6A-48BA-82C8-A13EEF94E11CQ33944293-3EEF2DF5-BDB5-4CF4-878D-268DCD46616EQ34193432-A49E5BAD-D06A-4FC2-9652-05BB6D27157AQ34286552-2FD3C924-4B3D-47EB-8B79-CDA5C78C33F8Q34583240-C23FAFD4-A120-4156-BC54-E2CC19CB0B54Q34642934-BCAA3C7A-51A5-4FD9-9E8B-EBE2DDC0B7C5Q34773978-8D03B169-CD36-4F26-ACBB-E872F86CA445Q35024532-7CE52DB5-B568-4DA2-A467-A37DA0989BD2Q35156186-FBC5855C-266F-45AC-B027-79706B2DFD66Q35566536-65F3FD17-81B0-429D-9C34-46274B29C66CQ35575376-209C7B67-D060-42CF-96A7-DF72AD5A7C59Q35636353-F1134922-619D-40A1-BC58-E7AC79F77E57Q35897933-E738CB0B-2F86-4090-B8C1-6B7C64664E6EQ36052549-BF688E1F-7EE0-4FED-83B2-D7FA1ABF44BCQ36121784-71104993-CEDB-4334-9D5D-4891D370E4CAQ36166645-AC3B8BE6-CC39-46F9-8300-AFC23AD9DF19Q36263703-3B31D0DE-E986-445E-A448-8CFD525A2307Q36328393-DB000EC4-0224-40FF-A0F9-4811C26EE65EQ36406816-92EA0242-2256-4A2D-A2D2-3473F7FEA79AQ36439458-A3D98813-17D7-45C2-B02D-7C0373913A6DQ36911581-A60B8DBE-5800-451F-84FD-6EBE245259F4Q37140411-B1B26D10-821C-46F1-B074-7B3442FEF669Q37169515-E339857D-EA38-45C1-AE76-9D7D1E0DD205Q37217417-358993B8-C93E-42C9-9ECB-84E30CA4DCDD
P2860
Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids.
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@ast
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@en
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@nl
type
label
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@ast
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@en
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@nl
prefLabel
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@ast
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@en
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@nl
P2093
P356
P1476
Deorphanization of GPRC6A: a p ...... ference for basic amino acids.
@en
P2093
Anders Balsgaard
Hans Bräuner-Osborne
Jan Egebjerg
Jeremy R Greenwood
Kasper B Hansen
Petrine Wellendorph
P304
P356
10.1124/MOL.104.007559
P577
2004-12-02T00:00:00Z