Targeting nrf2 signaling to combat chemoresistance. - Wikidata - awgldk - TriplyDB

Targeting nrf2 signaling to combat chemoresistance.

Targeting nrf2 signaling to combat chemoresistance.

http://www.wikidata.org/entity/Q34376139

about

ROS and Brain Gliomas: An Overview of Potential and Innovative Therapeutic Strategies Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications The role of quercetin and vitamin C in Nrf2-dependent oxidative stress production in breast cancer cells Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2 The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells.Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells Activated Nrf2 Interacts with Kaposi's Sarcoma-Associated Herpesvirus Latency Protein LANA-1 and Host Protein KAP1 To Mediate Global Lytic Gene Repression.Nrf2 activation as target to implement therapeutic treatments Nrf2: a potential therapeutic target for naturally occurring anticancer drugs?Growth inhibitory effect of β-eudesmol on cholangiocarcinoma cells and its potential suppressive effect on heme oxygenase-1 production, STAT1/3 activation, and NF-κB downregulation.Nobiletin enhances the efficacy of chemotherapeutic agents in ABCB1 overexpression cancer cells.Emerging role of NRF2 in chemoresistance by regulating drug-metabolizing enzymes and efflux transporters.ROS in Cancer: The Burning Question.Metformin Induces Cell Cycle Arrest and Apoptosis in Drug-Resistant Leukemia Cells.Activating de novo mutations in NFE2L2 encoding NRF2 cause a multisystem disorder.Redox-Related Epigenetic Mechanisms in Glioblastoma: Nuclear Factor (Erythroid-Derived 2)-Like 2, Cobalamin, and Dopamine Receptor Subtype 4 Dysregulation of NRF2 in Cancer: from Molecular Mechanisms to Therapeutic Opportunities.Repurposing of the CDK inhibitor PHA-767491 as a NRF2 inhibitor drug candidate for cancer therapy via redox modulation.The Role of Redox-Regulating Enzymes in Inoperable Breast Cancers Treated with Neoadjuvant Chemotherapy.Parthenolide prevents resistance of MDA-MB231 cells to doxorubicin and mitoxantrone: the role of Nrf2.UVA Irradiation Enhances Brusatol-Mediated Inhibition of Melanoma Growth by Downregulation of the Nrf2-Mediated Antioxidant Response.Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation A catalogue of somatic NRF2 gain-of-function mutations in cancer

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Targeting nrf2 signaling to combat chemoresistance.

http://www.wikidata.org/entity/Q34376139

description

2014 nî lūn-bûn

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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Targeting nrf2 signaling to combat chemoresistance.

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Targeting nrf2 signaling to combat chemoresistance.

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Targeting nrf2 signaling to combat chemoresistance.

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type

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Targeting nrf2 signaling to combat chemoresistance.

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Targeting nrf2 signaling to combat chemoresistance.

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Targeting nrf2 signaling to combat chemoresistance.

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Targeting nrf2 signaling to combat chemoresistance.

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Targeting nrf2 signaling to combat chemoresistance.

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Targeting nrf2 signaling to combat chemoresistance.

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JCP.2014.19.2.111

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Journal of cancer prevention

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Targeting nrf2 signaling to combat chemoresistance.

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Jae Hong No

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Yong Sang Song

http://www.w3.org/2001/XMLSchema#string

Yong-Beom Kim

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P2860

p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2

Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis

Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate

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