Mutants of Escherichia coli formylmethionine tRNA: a single base change enables initiator tRNA to act as an elongator in vitro
about
Striking effects of coupling mutations in the acceptor stem on recognition of tRNAs by Escherichia coli Met-tRNA synthetase and Met-tRNA transformylaseInitiator-elongator discrimination in vertebrate tRNAs for protein synthesis.Conformational change of Escherichia coli initiator methionyl-tRNA(fMet) upon binding to methionyl-tRNA formyl transferase.The tRNA specificity of Thermus thermophilus EF-Tu.Eukaryotic initiator tRNA: finely tuned and ready for action.Initiation of protein synthesis in bacteria.Biochemical characterization of pathogenic mutations in human mitochondrial methionyl-tRNA formyltransferaseOnce there were twenty.Induced fit of a peptide loop of methionyl-tRNA formyltransferase triggered by the initiator tRNA substrateFunctional consequences of T-stem mutations in E. coli tRNAThrUGU in vitro and in vivo.Codon reading scheme in Mycoplasma pneumoniae revealed by the analysis of the complete set of tRNA genesIs the sequence-specific binding of aminoacyl-tRNAs by EF-Tu universal among bacteria?The 51-63 base pair of tRNA confers specificity for binding by EF-TuAntideterminants present in minihelix(Sec) hinder its recognition by prokaryotic elongation factor Tu.NMR analysis of tRNA acceptor stem microhelices: discriminator base change affects tRNA conformation at the 3' endImportance of formylability and anticodon stem sequence to give a tRNA(Met) an initiator identity in Escherichia coli.Initiator transfer RNAs.Role of methionine and formylation of initiator tRNA in initiation of protein synthesis in Escherichia coliFrom elongator tRNA to initiator tRNA.The discriminator base influences tRNA structure at the end of the acceptor stem and possibly its interaction with proteinsEnzymatic aminoacylation of sequence-specific RNA minihelices and hybrid duplexes with methionine.Lysine 207 as the site of cross-linking between the 3'-end of Escherichia coli initiator tRNA and methionyl-tRNA formyltransferase.Mutational analysis of conserved positions potentially important for initiator tRNA function in Saccharomyces cerevisiaeUnderstanding the sequence specificity of tRNA binding to elongation factor Tu using tRNA mutagenesis.Anticodon-dependent aminoacylation of a noncognate tRNA with isoleucine, valine, and phenylalanine in vivo.The Escherichia coli argU10(Ts) phenotype is caused by a reduction in the cellular level of the argU tRNA for the rare codons AGA and AGG.Many of the conserved nucleotides of tRNA(Phe) are not essential for ternary complex formation and peptide elongation.Mutants of Escherichia coli initiator tRNA that suppress amber codons in Saccharomyces cerevisiae and are aminoacylated with tyrosine by yeast extracts.Initiation of protein synthesis from a termination codon.Characterization of 16S rRNA mutations that decrease the fidelity of translation initiation.Escherichia coli initiator tRNA: structure-function relationships and interactions with the translational machinery.Highly chromophoric Cy5-methionine for N-terminal fluorescent tagging of proteins in eukaryotic translation systemsIs the cellular initiation of translation an exclusive property of the initiator tRNAs?Initiation with elongator tRNAs.Yeast initiator tRNA identity elements cooperate to influence multiple steps of translation initiation.Common location of determinants in initiator transfer RNAs for initiator-elongator discrimination in bacteria and in eukaryotes.Messing up translation from the start: how AtaT inhibits translation initiation in E. coli.A G.U base pair in the eukaryotic selenocysteine tRNA is important for interaction with SePF, the putative selenocysteine-specific elongation factor.The fate of the initiator tRNAs is sensitive to the critical balance between interacting proteins.Two highly conserved features of bacterial initiator tRNAs license them to pass through distinct checkpoints in translation initiation.
P2860
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P2860
Mutants of Escherichia coli formylmethionine tRNA: a single base change enables initiator tRNA to act as an elongator in vitro
description
1987 nî lūn-bûn
@nan
1987 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@ast
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@en
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@nl
type
label
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@ast
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@en
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@nl
prefLabel
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@ast
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@en
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@nl
P2860
P356
P1476
Mutants of Escherichia coli fo ...... o act as an elongator in vitro
@en
P2093
U L RajBhandary
P2860
P304
P356
10.1073/PNAS.84.24.8859
P407
P577
1987-12-01T00:00:00Z