Human immunodeficiency virus protease expressed in Escherichia coli exhibits autoprocessing and specific maturation of the gag precursor.
about
Molecular and biotechnological aspects of microbial proteasesActivity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptidesActive human immunodeficiency virus protease is required for viral infectivityHuman immunodeficiency virus has an aspartic-type protease that can be inhibited by pepstatin ACrystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: Insights into the mechanisms of drug resistanceStructure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallographyThe aspartic proteasesHuman immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cellsIncorporation of 12-methoxydodecanoate into the human immunodeficiency virus 1 gag polyprotein precursor inhibits its proteolytic processing and virus production in a chronically infected human lymphoid cell lineInhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitorsChemical synthesis and enzymatic activity of a 99-residue peptide with a sequence proposed for the human immunodeficiency virus proteaseIn vitro anti-human immunodeficiency virus (HIV) activity of XM323, a novel HIV protease inhibitorMolecular modeling studies suggest that zinc ions inhibit HIV-1 protease by binding at catalytic aspartatesEfficacy of constant infusion of A-77003, an inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, in limiting acute HIV-1 infection in vitroGag-Pol processing during HIV-1 virion maturation: a systems biology approachMouse homologue of skin-specific retroviral-like aspartic protease involved in wrinkle formationNucleotide sequence and genomic organization of feline immunodeficiency virus.The central domain of the matrix protein of HIV-1: influence on protein structure and virus infectivity.Requirements for incorporation of Pr160gag-pol from human immunodeficiency virus type 1 into virus-like particles.Thermodynamic linkage between the binding of protons and inhibitors to HIV-1 protease.Characterization of a discontinuous epitope of the human immunodeficiency virus (HIV) core protein p24 by epitope excision and differential chemical modification followed by mass spectrometric peptide mapping analysisUnderstanding HIV-1 protease autoprocessing for novel therapeutic development.Identification of structural mechanisms of HIV-1 protease specificity using computational peptide docking: implications for drug resistance.Isolation of mutants of human immunodeficiency virus protease based on the toxicity of the enzyme in Escherichia coli.Human immunodeficiency virus type 1 protease cleaves the intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein.Trans-dominant inhibitory human immunodeficiency virus type 1 protease monomers prevent protease activation and virion maturation.Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease.Efficient identification of human immunodeficiency virus type 1 mutants resistant to a protease inhibitor by using a random mutant library.Production of active mammalian and viral proteases in bacterial expression systems.Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector.Clinical pharmacology and pharmacokinetics of amprenavir.Human immunodeficiency virus type 1 Gag proteins are processed in two cellular compartments.Human serum alpha 1 acid glycoprotein reduces uptake, intracellular concentration, and antiviral activity of A-80987, an inhibitor of the human immunodeficiency virus type 1 protease.The SIVmac239 Pr55Gag isoform, SIV p43, suppresses proteolytic cleavage of Pr55Gag.Validating the vitality strategy for fighting drug resistance.Inhibition of human and simian immunodeficiency virus protease function by targeting Vpx-protease-mutant fusion protein into viral particlesA p6Pol-protease fusion protein is present in mature particles of human immunodeficiency virus type 1.The Race against Protease Activation Defines the Role of ESCRTs in HIV BuddingEffect of linker insertion mutations in the human immunodeficiency virus type 1 gag gene on activation of viral protease expressed in bacteriaMutational analysis of human immunodeficiency virus type 1 protease suggests functional homology with aspartic proteinases
P2860
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P2860
Human immunodeficiency virus protease expressed in Escherichia coli exhibits autoprocessing and specific maturation of the gag precursor.
description
1987 nî lūn-bûn
@nan
1987 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
name
Human immunodeficiency virus p ...... turation of the gag precursor.
@ast
Human immunodeficiency virus p ...... turation of the gag precursor.
@en
Human immunodeficiency virus p ...... turation of the gag precursor.
@nl
type
label
Human immunodeficiency virus p ...... turation of the gag precursor.
@ast
Human immunodeficiency virus p ...... turation of the gag precursor.
@en
Human immunodeficiency virus p ...... turation of the gag precursor.
@nl
prefLabel
Human immunodeficiency virus p ...... turation of the gag precursor.
@ast
Human immunodeficiency virus p ...... turation of the gag precursor.
@en
Human immunodeficiency virus p ...... turation of the gag precursor.
@nl
P2093
P2860
P356
P1476
Human immunodeficiency virus p ...... turation of the gag precursor.
@en
P2093
B W Metcalf
J E Strickler
J G Gorniak
M Rosenberg
P2860
P304
P356
10.1073/PNAS.84.24.8903
P407
P577
1987-12-01T00:00:00Z