Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis.
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The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repressionIs evolution Darwinian or/and Lamarckian?Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancyContribution of the Type II Chaperonin, TRiC/CCT, to OncogenesisPushing tumor cells towards a malignant phenotype: stimuli from the microenvironment, intercellular communications and alternative roadsCaught in the cross fire: p53 in inflammation.Janus-faced tumor microenvironment and redoxThe yeast environmental stress response regulates mutagenesis induced by proteotoxic stressInhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130.VEGFR2 heterogeneity and response to anti-angiogenic low dose metronomic cyclophosphamide treatment.Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1Evolutionary dynamics of carcinogenesis and why targeted therapy does not work.Metastasis in melanoma xenografts is associated with tumor microvascular density rather than extent of hypoxia.Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistanceEnvironmental stress induces trinucleotide repeat mutagenesis in human cells.Tumor heterogeneity: mechanisms and bases for a reliable application of molecular marker designDown-regulation of ANAPC13 and CLTCL1: Early Events in the Progression of Preinvasive Ductal Carcinoma of the Breast.Genome-independent hypoxic repression of estrogen receptor alpha in breast cancer cells.A principle of organization which facilitates broad Lamarckian-like adaptations by improvisationpH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents.Metastasis: recent discoveries and novel treatment strategies.Molecular targeting of liposomal nanoparticles to tumor microenvironment.Hypoxia-induced genetic instability--a calculated mechanism underlying tumor progression.Hypoxia, gene expression, and metastasis.The evolving concept of tumor microenvironments.E2F4 regulates a stable G2 arrest response to genotoxic stress in prostate carcinomaWhat is the malignant nature of human ductal carcinoma in situ?miRNA modulation of the cellular stress response.Attacking breast cancer at the preinvasion stage by targeting autophagy.C-1027, a radiomimetic enediyne anticancer drug, preferentially targets hypoxic cellsNiche contributions to oncogenesis: emerging concepts and implications for the hematopoietic system.Nanopreparations to overcome multidrug resistance in cancer.Caveolin-1 in oral squamous cell carcinoma microenvironment: an overview.Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironmentHypoxia and DNA repair.Hypoxia and human genome stability: downregulation of BRCA2 expression in breast cancer cell lines.Acidic tumor microenvironment downregulates hMLH1 but does not diminish 5-fluorouracil chemosensitivity.Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter.ATM activation and signaling under hypoxic conditions.Hypoxia upregulates carcinoembryonic antigen expression in cancer cells.
P2860
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P2860
Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Genetic instability and the tu ...... vironment-induced mutagenesis.
@ast
Genetic instability and the tu ...... vironment-induced mutagenesis.
@en
Genetic instability and the tu ...... vironment-induced mutagenesis.
@nl
type
label
Genetic instability and the tu ...... vironment-induced mutagenesis.
@ast
Genetic instability and the tu ...... vironment-induced mutagenesis.
@en
Genetic instability and the tu ...... vironment-induced mutagenesis.
@nl
prefLabel
Genetic instability and the tu ...... vironment-induced mutagenesis.
@ast
Genetic instability and the tu ...... vironment-induced mutagenesis.
@en
Genetic instability and the tu ...... vironment-induced mutagenesis.
@nl
P1433
P1476
Genetic instability and the tu ...... vironment-induced mutagenesis.
@en
P2093
Peter M Glazer
Ranjit S Bindra
P356
10.1016/J.MRFMMM.2004.03.013
P407
P577
2005-01-01T00:00:00Z