RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media
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Phylogenomic analyses of nuclear genes reveal the evolutionary relationships within the BEP clade and the evidence of positive selection in PoaceaeElucidating the molecular architecture of adaptation via evolve and resequence experimentsCellular Growth Arrest and Persistence from Enzyme SaturationCosts of antibiotic resistance - separating trait effects and selective effectsTranshydrogenase promotes the robustness and evolvability of E. coli deficient in NADPH productionParallel and Divergent Evolutionary Solutions for the Optimization of an Engineered Central Metabolism in Methylobacterium extorquens AM1Tangled bank of experimentally evolved Burkholderia biofilms reflects selection during chronic infectionsExperimental evolution of enhanced growth by Bacillus subtilis at low atmospheric pressure: genomic changes revealed by whole-genome sequencing.Evolved osmotolerant Escherichia coli mutants frequently exhibit defective N-acetylglucosamine catabolism and point mutations in cell shape-regulating protein MreB.The role of cellular objectives and selective pressures in metabolic pathway evolution.An insertion in the catalytic trigger loop gates the secondary channel of RNA polymerase.Experimental Evolution of Metabolic Dependency in Bacteria.Short-term differential adaptation to anaerobic stress via genomic mutations by Escherichia coli strains K-12 and B lacking alcohol dehydrogenase.Evolution of Escherichia coli to 42 °C and subsequent genetic engineering reveals adaptive mechanisms and novel mutations.Fitness landscape transformation through a single amino acid change in the rho terminator.Significant rewiring of the transcriptome and proteome of an Escherichia coli strain harboring a tailored exogenous global regulator IrrE.Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase.Mutations in the primary sigma factor σA and termination factor rho that reduce susceptibility to cell wall antibiotics.Evolution of Escherichia coli rifampicin resistance in an antibiotic-free environment during thermal stressUse of adaptive laboratory evolution to discover key mutations enabling rapid growth of Escherichia coli K-12 MG1655 on glucose minimal mediumFunctional and metabolic effects of adaptive glycerol kinase (GLPK) mutants in Escherichia coli.Rapid evolution of silver nanoparticle resistance in Escherichia coli.Microbial laboratory evolution in the era of genome-scale science.Gene order and chromosome dynamics coordinate spatiotemporal gene expression during the bacterial growth cycle.First-Step Mutations during Adaptation Restore the Expression of Hundreds of Genes.A mutation of the RNA polymerase β' subunit (rpoC) confers cephalosporin resistance in Bacillus subtilis.Characterization of the effects of an rpoC mutation that confers resistance to the Fst peptide toxin-antitoxin system toxin.Global Rebalancing of Cellular Resources by Pleiotropic Point Mutations Illustrates a Multi-scale Mechanism of Adaptive Evolution.The impact of drug resistance on Mycobacterium tuberculosis physiology: what can we learn from rifampicin?Deciphering the regulatory codes in bacterial genomes.Evolutionary insight from whole-genome sequencing of experimentally evolved microbes.New insights into bacterial adaptation through in vivo and in silico experimental evolution.Integration of syntactic and semantic properties of the DNA code reveals chromosomes as thermodynamic machines converting energy into information.Adaptive laboratory evolution -- principles and applications for biotechnology.Expanding the metabolic engineering toolbox with directed evolution.Analyzing the genomic variation of microbial cell factories in the era of "New Biotechnology".The adaptive landscape of wildtype and glycosylation-deficient populations of the industrial yeast Pichia pastoris.Laboratory Evolution to Alternating Substrate Environments Yields Distinct Phenotypic and Genetic Adaptive Strategies.Determination of single nucleotide variants in Escherichia coli DH5α by using short-read sequencing.Evolutionary potential, cross-stress behavior and the genetic basis of acquired stress resistance in Escherichia coli.
P2860
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P2860
RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
RNA polymerase mutants found t ...... ptimal growth in minimal media
@ast
RNA polymerase mutants found t ...... ptimal growth in minimal media
@en
RNA polymerase mutants found t ...... ptimal growth in minimal media
@nl
type
label
RNA polymerase mutants found t ...... ptimal growth in minimal media
@ast
RNA polymerase mutants found t ...... ptimal growth in minimal media
@en
RNA polymerase mutants found t ...... ptimal growth in minimal media
@nl
prefLabel
RNA polymerase mutants found t ...... ptimal growth in minimal media
@ast
RNA polymerase mutants found t ...... ptimal growth in minimal media
@en
RNA polymerase mutants found t ...... ptimal growth in minimal media
@nl
P2093
P2860
P356
P1476
RNA polymerase mutants found t ...... ptimal growth in minimal media
@en
P2093
Andrew R Joyce
Byung-Kwan Cho
Eric M Knight
Michael Frazier
Robert Landick
Tom M Conrad
P2860
P304
20500-20505
P356
10.1073/PNAS.0911253107
P407
P577
2010-11-05T00:00:00Z